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Obesity Reduces Bone Density Associated with Activation of PPARγ and Suppression of Wnt/β-Catenin in Rapidly Growing Male Rats
BACKGROUND: It is well established that excessive consumption of a high fat diet (HFD) results in obesity; however, the consequences of obesity on postnatal skeletal development have not been well studied. METHODOLOGY AND PRINCIPAL FINDINGS: Total enteral nutrition (TEN) was used to feed postnatal d...
Autores principales: | Chen, Jin-Ran, Lazarenko, Oxana P., Wu, Xianli, Tong, Yudong, Blackburn, Michael L., Shankar, Kartik, Badger, Thomas M., Ronis, Martin J. J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965663/ https://www.ncbi.nlm.nih.gov/pubmed/21060836 http://dx.doi.org/10.1371/journal.pone.0013704 |
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