Point Mutations in c-Myc Uncouple Neoplastic Transformation from Multiple Other Phenotypes in Rat Fibroblasts

Deregulation of c-Myc (Myc) occurs in many cancers. In addition to transforming various cell types, Myc also influences additional transformation-associated cellular phenotypes including proliferation, survival, genomic instability, reactive oxygen species production, and metabolism. Although Myc is...

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Detalles Bibliográficos
Autores principales: Graves, J. Anthony, Rothermund, Kristi, Wang, Tao, Qian, Wei, Van Houten, Bennett, Prochownik, Edward V.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965668/
https://www.ncbi.nlm.nih.gov/pubmed/21060841
http://dx.doi.org/10.1371/journal.pone.0013717

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965668/
https://www.ncbi.nlm.nih.gov/pubmed/21060841
http://dx.doi.org/10.1371/journal.pone.0013717

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