Cell Type-Specific Neuroprotective Activity of Untranslocated Prion Protein

BACKGROUND: A key pathogenic role in prion diseases was proposed for a cytosolic form of the prion protein (PrP). However, it is not clear how cytosolic PrP localization influences neuronal viability, with either cytotoxic or anti-apoptotic effects reported in different studies. The cellular mechani...

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Detalles Bibliográficos
Autores principales: Restelli, Elena, Fioriti, Luana, Mantovani, Susanna, Airaghi, Simona, Forloni, Gianluigi, Chiesa, Roberto
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965675/
https://www.ncbi.nlm.nih.gov/pubmed/21060848
http://dx.doi.org/10.1371/journal.pone.0013725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965675/
https://www.ncbi.nlm.nih.gov/pubmed/21060848
http://dx.doi.org/10.1371/journal.pone.0013725

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