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Cell Type-Specific Neuroprotective Activity of Untranslocated Prion Protein
BACKGROUND: A key pathogenic role in prion diseases was proposed for a cytosolic form of the prion protein (PrP). However, it is not clear how cytosolic PrP localization influences neuronal viability, with either cytotoxic or anti-apoptotic effects reported in different studies. The cellular mechani...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965675/ https://www.ncbi.nlm.nih.gov/pubmed/21060848 http://dx.doi.org/10.1371/journal.pone.0013725 |