Cargando…

Nutrient Control of Yeast PKA Activity Involves Opposing Effects on Phosphorylation of the Bcy1 Regulatory Subunit

GPB1 and GPB2 encode kelch repeat-containing proteins that regulate protein kinase A (PKA) in yeast by a cAMP-independent process. Here we show that Gpb1 and Gpb2 stimulate phosphorylation of PKA regulatory subunit Bcy1 in low glucose concentrations, thereby promoting the inhibitory function of Bcy1...

Descripción completa

Detalles Bibliográficos
Autores principales:	Budhwar, Roli, Lu, Ailan, Hirsch, Jeanne P.
Formato:	Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2010
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965690/ https://www.ncbi.nlm.nih.gov/pubmed/20826609 http://dx.doi.org/10.1091/mbc.E10-05-0388

Ejemplares similares

PKA regulatory subunit Bcy1 couples growth, lipid metabolism, and fermentation during anaerobic xylose growth in Saccharomyces cerevisiae
por: Wagner, Ellen R., et al.
Publicado: (2023)

Phosphorylation of protein kinase A (PKA) regulatory subunit RIα by protein kinase G (PKG) primes PKA for catalytic activity in cells
por: Haushalter, Kristofer J., et al.
Publicado: (2018)

PKA regulation of neuronal function requires the dissociation of catalytic subunits from regulatory subunits
por: Xiong, Wei-Hong, et al.
Publicado: (2023)

Nutrient Control of Yeast Gametogenesis Is Mediated by TORC1, PKA and Energy Availability
por: Weidberg, Hilla, et al.
Publicado: (2016)

In Vivo Phosphorylation of Ser(21) and Ser(83) during Nutrient-induced Activation of the Yeast Protein Kinase A (PKA) Target Trehalase
por: Schepers, Wim, et al.
Publicado: (2012)

PKA-RII subunit phosphorylation precedes activation by cAMP and regulates activity termination
por: Isensee, Jörg, et al.
Publicado: (2018)

Phosphorylation and Dephosphorylation of Tau Protein by the Catalytic Subunit of PKA, as Probed by Electrophoretic Mobility Retard
por: Benítez, María J., et al.
Publicado: (2021)

PKA regulatory IIα subunit is essential for PGD(2)-mediated resolution of inflammation
por: Kong, Deping, et al.
Publicado: (2016)

Regulatory subunits of PKA define an axis of cellular proliferation/differentiation in ovarian cancer cells
por: Cheadle, Chris, et al.
Publicado: (2008)

Plasmodium falciparum Regulatory Subunit of cAMP-Dependent PKA and Anion Channel Conductance
por: Merckx, Anaïs, et al.
Publicado: (2008)

PKA regulatory subunit R2B is required for murine and human adipocyte differentiation
por: Peverelli, Erika, et al.
Publicado: (2013)

PKA Cα subunit mutation triggers caspase-dependent RIIβ subunit degradation via Ser(114) phosphorylation
por: Weigand, Isabel, et al.
Publicado: (2021)

PKA regulatory subunits mediate synergy among conserved G-protein-coupled receptor cascades
por: Stefan, Eduard, et al.
Publicado: (2011)

The testis-specific Cα2 subunit of PKA is kinetically indistinguishable from the common Cα1 subunit of PKA
por: Vetter, Maike M, et al.
Publicado: (2011)

Opposing regulatory roles of phosphorylation and acetylation in DNA mispair processing by thymine DNA glycosylase
por: Mohan, Ryan D., et al.
Publicado: (2010)

Nutrient Sensing Kinases PKA and Sch9 Phosphorylate the Catalytic Domain of the Ubiquitin-Conjugating Enzyme Cdc34
por: Cocklin, Ross, et al.
Publicado: (2011)

Nutrient sensing and cAMP signaling in yeast: G-protein coupled receptor versus transceptor activation of PKA
por: Van Zeebroeck, Griet, et al.
Publicado: (2020)

The Regulatory Subunit of PKA-I Remains Partially Structured and Undergoes β-Aggregation upon Thermal Denaturation
por: Dao, Khanh K., et al.
Publicado: (2011)

Loss of PKA regulatory subunit 1α aggravates cardiomyocyte necrosis and myocardial ischemia/reperfusion injury
por: Liu, Yuening, et al.
Publicado: (2021)

Opposing Roles of pka and epac in the cAMP-Dependent Regulation of Schwann Cell Proliferation and Differentiation
por: Bacallao, Ketty, et al.
Publicado: (2013)

RNA-Sequencing of Heterorhabditis nematodes to identify factors involved in symbiosis with Photorhabdus bacteria
por: Bhat, Chaitra G., et al.
Publicado: (2022)

Transcription levels of a noncoding RNA orchestrate opposing regulatory and cell fate outcomes in yeast
por: Moretto, Fabien, et al.
Publicado: (2021)

Correction: Opposing Roles of pka and epac in the cAMP-Dependent Regulation of Schwann Cell Proliferation and Differentiation
por: Bacallao, Ketty, et al.
Publicado: (2014)

Opposing Roles of FACT for Euchromatin and Heterochromatin in Yeast
por: Takahata, Shinya, et al.
Publicado: (2023)

STIM2 regulates PKA-dependent phosphorylation and trafficking of AMPARs
por: Garcia-Alvarez, Gisela, et al.
Publicado: (2015)

Regulatory B Subunits of Protein Phosphatase 2A Are Involved in Site-specific Regulation of Tau Protein Phosphorylation
por: Yu, Un Young, et al.
Publicado: (2014)

Integrated transcriptomics and miRNAomics provide insights into the complex multi-tiered regulatory networks associated with coleoptile senescence in rice
por: Sasi, Jyothish Madambikattil, et al.
Publicado: (2022)

Corrigendum: Integrated transcriptomics and miRNAomics provide insights into the complex multi-tiered regulatory networks associated with coleoptile senescence in rice
por: Sasi, Jyothish Madambikattil, et al.
Publicado: (2023)

The Catalytic Subunit β of PKA Affects Energy Balance and Catecholaminergic Activity
por: London, Edra, et al.
Publicado: (2019)

The Hybrid BCI
por: Pfurtscheller, Gert, et al.
Publicado: (2010)

Model-guided optogenetic study of PKA signaling in budding yeast
por: Stewart-Ornstein, Jacob, et al.
Publicado: (2017)

PKA isoforms coordinate mRNA fate during nutrient starvation
por: Tudisca, Vanesa, et al.
Publicado: (2012)

Disease from opposing forces in regulatory control
por: Frank, Steven A
Publicado: (2023)

Sir2 phosphorylation through cAMP-PKA and CK2 signaling inhibits the lifespan extension activity of Sir2 in yeast
por: Kang, Woo Kyu, et al.
Publicado: (2015)

The Regulatory Subunit of Protein Kinase A (Bcy1) in Candida albicans Plays Critical Roles in Filamentation and White-Opaque Switching but Is Not Essential for Cell Growth
por: Ding, Xuefen, et al.
Publicado: (2017)

Two adjacent phosphorylation sites in the C-terminus of the channel’s α-subunit have opposing effects on epithelial sodium channel (ENaC) activity
por: Diakov, Alexei, et al.
Publicado: (2022)

Transient Calcium and Dopamine Increase PKA Activity and DARPP-32 Phosphorylation
por: Lindskog, Maria, et al.
Publicado: (2006)

STK25 inhibits PKA signaling by phosphorylating PRKAR1A
por: Zhang, Xiaokan, et al.
Publicado: (2022)

Evolutionary Paths of the cAMP-Dependent Protein Kinase (PKA) Catalytic Subunits
por: Søberg, Kristoffer, et al.
Publicado: (2013)

Evolution of the cAMP-dependent protein kinase (PKA) catalytic subunit isoforms
por: Søberg, Kristoffer, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_kbk9g4o038md5ap0hmvgsdblga