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Numerical Analysis of Ca(2+) Signaling in Rat Ventricular Myocytes with Realistic Transverse-Axial Tubular Geometry and Inhibited Sarcoplasmic Reticulum

The t-tubules of mammalian ventricular myocytes are invaginations of the cell membrane that occur at each Z-line. These invaginations branch within the cell to form a complex network that allows rapid propagation of the electrical signal, and hence synchronous rise of intracellular calcium (Ca(2+))....

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Detalles Bibliográficos
Autores principales:	Cheng, Yuhui, Yu, Zeyun, Hoshijima, Masahiko, Holst, Michael J., McCulloch, Andrew D., McCammon, J. Andrew, Michailova, Anushka P.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965743/ https://www.ncbi.nlm.nih.gov/pubmed/21060856 http://dx.doi.org/10.1371/journal.pcbi.1000972

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