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Continuous Requirement for the Clr4 Complex But Not RNAi for Centromeric Heterochromatin Assembly in Fission Yeast Harboring a Disrupted RITS Complex

Formation of centromeric heterochromatin in fission yeast requires the combined action of chromatin modifying enzymes and small RNAs derived from centromeric transcripts. Positive feedback mechanisms that link the RNAi pathway and the Clr4/Suv39h1 histone H3K9 methyltransferase complex (Clr-C) resul...

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Detalles Bibliográficos
Autores principales:	Shanker, Sreenath, Job, Godwin, George, Olivia L., Creamer, Kevin M., Shaban, Alaa, Partridge, Janet F.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965749/ https://www.ncbi.nlm.nih.gov/pubmed/21060862 http://dx.doi.org/10.1371/journal.pgen.1001174

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