Four Novel Loci (19q13, 6q24, 12q24, and 5q14) Influence the Microcirculation In Vivo

There is increasing evidence that the microcirculation plays an important role in the pathogenesis of cardiovascular diseases. Changes in retinal vascular caliber reflect early microvascular disease and predict incident cardiovascular events. We performed a genome-wide association study to identify...

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Detalles Bibliográficos
Autores principales: Ikram, M. Kamran, Xueling, Sim, Jensen, Richard A., Cotch, Mary Frances, Hewitt, Alex W., Ikram, M. Arfan, Wang, Jie Jin, Klein, Ronald, Klein, Barbara E. K., Breteler, Monique M. B., Cheung, Ning, Liew, Gerald, Mitchell, Paul, Uitterlinden, Andre G., Rivadeneira, Fernando, Hofman, Albert, de Jong, Paulus T. V. M., van Duijn, Cornelia M., Kao, Linda, Cheng, Ching-Yu, Smith, Albert Vernon, Glazer, Nicole L., Lumley, Thomas, McKnight, Barbara, Psaty, Bruce M., Jonasson, Fridbert, Eiriksdottir, Gudny, Aspelund, Thor, Harris, Tamara B., Launer, Lenore J., Taylor, Kent D., Li, Xiaohui, Iyengar, Sudha K., Xi, Quansheng, Sivakumaran, Theru A., Mackey, David A., MacGregor, Stuart, Martin, Nicholas G., Young, Terri L., Bis, Josh C., Wiggins, Kerri L., Heckbert, Susan R., Hammond, Christopher J., Andrew, Toby, Fahy, Samantha, Attia, John, Holliday, Elizabeth G., Scott, Rodney J., Islam, F. M. Amirul, Rotter, Jerome I., McAuley, Annie K., Boerwinkle, Eric, Tai, E. Shyong, Gudnason, Vilmundur, Siscovick, David S., Vingerling, Johannes R., Wong, Tien Y.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965750/
https://www.ncbi.nlm.nih.gov/pubmed/21060863
http://dx.doi.org/10.1371/journal.pgen.1001184

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