Inhibition of Nipah Virus Infection In Vivo: Targeting an Early Stage of Paramyxovirus Fusion Activation during Viral Entry

In the paramyxovirus cell entry process, receptor binding triggers conformational changes in the fusion protein (F) leading to viral and cellular membrane fusion. Peptides derived from C-terminal heptad repeat (HRC) regions in F have been shown to inhibit fusion by preventing formation of the fusoge...

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Detalles Bibliográficos
Autores principales: Porotto, Matteo, Rockx, Barry, Yokoyama, Christine C., Talekar, Aparna, DeVito, Ilaria, Palermo, Laura M., Liu, Jie, Cortese, Riccardo, Lu, Min, Feldmann, Heinz, Pessi, Antonello, Moscona, Anne
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965769/
https://www.ncbi.nlm.nih.gov/pubmed/21060819
http://dx.doi.org/10.1371/journal.ppat.1001168

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