Cargando…
Modulation of melanoma cell phospholipid metabolism in response to heat shock protein 90 inhibition
Molecular chaperone heat shock protein 90 (Hsp90) inhibitors are promising targeted cancer therapeutic drugs, with the advantage that they deplete multiple oncogenic client proteins and modulate all the classical hallmarks of cancer. They are now in clinical trial and show potential for activity in...
Autores principales: | Beloueche-Babari, Mounia, Arunan, Vaitha, Jackson, L. Elizabeth, Perusinghe, Nina, Sharp, Swee Y., Workman, Paul, Leach, Martin O. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2965833/ https://www.ncbi.nlm.nih.gov/pubmed/21037799 |
Ejemplares similares
-
Detecting human melanoma cell re-differentiation following BRAF or heat shock protein 90 inhibition using photoacoustic and magnetic resonance imaging
por: Shah, Anant, et al.
Publicado: (2017) -
Increased inflammatory lipid metabolism and anaplerotic mitochondrial activation follow acquired resistance to vemurafenib in BRAF-mutant melanoma cells
por: Delgado-Goñi, Teresa, et al.
Publicado: (2019) -
Acquired resistance to EGFR tyrosine kinase inhibitors alters the metabolism of human head and neck squamous carcinoma cells and xenograft tumours
por: Beloueche-Babari, M, et al.
Publicado: (2015) -
Acute tumour response to the MEK1/2 inhibitor selumetinib (AZD6244, ARRY-142886) evaluated by non-invasive diffusion-weighted MRI
por: Beloueche-Babari, M, et al.
Publicado: (2013) -
Monocarboxylate transporter 1 blockade with AZD3965 inhibits lipid biosynthesis and increases tumour immune cell infiltration
por: Beloueche-Babari, Mounia, et al.
Publicado: (2020)