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Mutational Tuning of Galectin-3 Specificity and Biological Function

Galectins are defined by a conserved β-galactoside binding site that has been linked to many of their important functions in e.g. cell adhesion, signaling, and intracellular trafficking. Weak adjacent sites may enhance or decrease affinity for natural β-galactoside-containing glycoconjugates, but li...

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Detalles Bibliográficos
Autores principales:	Salomonsson, Emma, Carlsson, Michael C., Osla, Veronica, Hendus-Altenburger, Ruth, Kahl-Knutson, Barbro, Öberg, Christopher T., Sundin, Anders, Nilsson, Rickard, Nordberg-Karlsson, Eva, Nilsson, Ulf J., Karlsson, Anna, Rini, James M., Leffler, Hakon
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2010
Materias:	Glycobiology and Extracellular Matrices
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966122/ https://www.ncbi.nlm.nih.gov/pubmed/20807768 http://dx.doi.org/10.1074/jbc.M109.098160

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