Cargando…
Lamin B Counteracts the Kinesin Eg5 to Restrain Spindle Pole Separation during Spindle Assembly
Lamin B is a component of the membranous spindle matrix isolated from Xenopus egg extracts, and it is required for proper spindle morphogenesis. Besides lamin B, the spindle matrix contains spindle assembly factors (SAFs) such as Eg5 and dynein which are known to regulate microtubule organization an...
Autores principales: | Goodman, Benjamin, Channels, Wilbur, Qiu, Minhua, Iglesias, Pablo, Yang, Ge, Zheng, Yixian |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966137/ https://www.ncbi.nlm.nih.gov/pubmed/20826821 http://dx.doi.org/10.1074/jbc.M110.140749 |
Ejemplares similares
-
Kinesin-5 Eg5 is essential for spindle assembly and chromosome alignment of mouse spermatocytes
por: She, Zhen-Yu, et al.
Publicado: (2020) -
Kinesin-5 Eg5 is essential for spindle assembly, chromosome stability and organogenesis in development
por: Yu, Wen-Xin, et al.
Publicado: (2022) -
Probing Spindle Assembly Mechanisms with Monastrol, a Small Molecule Inhibitor of the Mitotic Kinesin, Eg5
por: Kapoor, Tarun M., et al.
Publicado: (2000) -
Identification of a Novel Dynein Binding Domain in Nudel Essential for Spindle Pole Organization in Xenopus Egg Extract
por: Wang, Shusheng, et al.
Publicado: (2011) -
Tiam1-Rac Signaling Counteracts Eg5 during Bipolar Spindle Assembly to Facilitate Chromosome Congression
por: Woodcock, Simon A., et al.
Publicado: (2010)