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Molecular Detection of Targeted Major Histocompatibility Complex I-Bound Peptides Using a Probabilistic Measure and Nanospray MS(3) on a Hybrid Quadrupole-Linear Ion Trap

A nanospray MS(3) method deployed on a quadrupole linear ion trap hybrid can detect targeted peptides with high dynamic range and high sensitivity from complex mixtures without separations. The method uses a recognition algorithm that is a modification of the relative (Kullback−Leibler, KL) entropy...

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Detalles Bibliográficos
Autores principales:	Reinhold, Bruce, Keskin, Derin B., Reinherz, Ellis L.
Formato:	Texto
Lenguaje:	English
Publicado:	American Chemical Society 2010
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966287/ https://www.ncbi.nlm.nih.gov/pubmed/20932029 http://dx.doi.org/10.1021/ac102387t

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