Characterization of Human Huntington's Disease Cell Model from Induced Pluripotent Stem Cells

Huntington’s disease (HD) is a dominantly inherited neurodegenerative disease caused by a CAG repeat expansion in the first exon of the gene Huntingtin (Htt). A dramatic pathological change in HD is the massive loss of striatal neurons as the disease progresses. A useful advance in HD would be the g...

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Detalles Bibliográficos
Autores principales: Zhang, Ningzhe, An, Mahru C., Montoro, Daniel, Ellerby, Lisa M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Huntington Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966296/
https://www.ncbi.nlm.nih.gov/pubmed/21037797
http://dx.doi.org/10.1371/currents.RRN1193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966296/
https://www.ncbi.nlm.nih.gov/pubmed/21037797
http://dx.doi.org/10.1371/currents.RRN1193

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