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Prevalence and Phylogeny of Coronaviruses in Wild Birds from the Bering Strait Area (Beringia)

Coronaviruses (CoVs) can cause mild to severe disease in humans and animals, their host range and environmental spread seem to have been largely underestimated, and they are currently being investigated for their potential medical relevance. Infectious bronchitis virus (IBV) belongs to gamma-coronav...

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Autores principales: Muradrasoli, Shaman, Bálint, Ádám, Wahlgren, John, Waldenström, Jonas, Belák, Sándor, Blomberg, Jonas, Olsen, Björn
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966397/
https://www.ncbi.nlm.nih.gov/pubmed/21060827
http://dx.doi.org/10.1371/journal.pone.0013640
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author Muradrasoli, Shaman
Bálint, Ádám
Wahlgren, John
Waldenström, Jonas
Belák, Sándor
Blomberg, Jonas
Olsen, Björn
author_facet Muradrasoli, Shaman
Bálint, Ádám
Wahlgren, John
Waldenström, Jonas
Belák, Sándor
Blomberg, Jonas
Olsen, Björn
author_sort Muradrasoli, Shaman
collection PubMed
description Coronaviruses (CoVs) can cause mild to severe disease in humans and animals, their host range and environmental spread seem to have been largely underestimated, and they are currently being investigated for their potential medical relevance. Infectious bronchitis virus (IBV) belongs to gamma-coronaviruses and causes a costly respiratory viral disease in chickens. The role of wild birds in the epidemiology of IBV is poorly understood. In the present study, we examined 1,002 cloacal and faecal samples collected from 26 wild bird species in the Beringia area for the presence of CoVs, and then we performed statistical and phylogenetic analyses. We detected diverse CoVs by RT-PCR in wild birds in the Beringia area. Sequence analysis showed that the detected viruses are gamma-coronaviruses related to IBV. These findings suggest that wild birds are able to carry gamma-coronaviruses asymptomatically. We concluded that CoVs are widespread among wild birds in Beringia, and their geographic spread and frequency is higher than previously realised. Thus, Avian CoV can be efficiently disseminated over large distances and could be a genetic reservoir for future emerging pathogenic CoVs. Considering the great animal health and economic impact of IBV as well as the recent emergence of novel coronaviruses such as SARS-coronavirus, it is important to investigate the role of wildlife reservoirs in CoV infection biology and epidemiology.
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spelling pubmed-29663972010-11-08 Prevalence and Phylogeny of Coronaviruses in Wild Birds from the Bering Strait Area (Beringia) Muradrasoli, Shaman Bálint, Ádám Wahlgren, John Waldenström, Jonas Belák, Sándor Blomberg, Jonas Olsen, Björn PLoS One Research Article Coronaviruses (CoVs) can cause mild to severe disease in humans and animals, their host range and environmental spread seem to have been largely underestimated, and they are currently being investigated for their potential medical relevance. Infectious bronchitis virus (IBV) belongs to gamma-coronaviruses and causes a costly respiratory viral disease in chickens. The role of wild birds in the epidemiology of IBV is poorly understood. In the present study, we examined 1,002 cloacal and faecal samples collected from 26 wild bird species in the Beringia area for the presence of CoVs, and then we performed statistical and phylogenetic analyses. We detected diverse CoVs by RT-PCR in wild birds in the Beringia area. Sequence analysis showed that the detected viruses are gamma-coronaviruses related to IBV. These findings suggest that wild birds are able to carry gamma-coronaviruses asymptomatically. We concluded that CoVs are widespread among wild birds in Beringia, and their geographic spread and frequency is higher than previously realised. Thus, Avian CoV can be efficiently disseminated over large distances and could be a genetic reservoir for future emerging pathogenic CoVs. Considering the great animal health and economic impact of IBV as well as the recent emergence of novel coronaviruses such as SARS-coronavirus, it is important to investigate the role of wildlife reservoirs in CoV infection biology and epidemiology. Public Library of Science 2010-10-29 /pmc/articles/PMC2966397/ /pubmed/21060827 http://dx.doi.org/10.1371/journal.pone.0013640 Text en Muradrasoli et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Muradrasoli, Shaman
Bálint, Ádám
Wahlgren, John
Waldenström, Jonas
Belák, Sándor
Blomberg, Jonas
Olsen, Björn
Prevalence and Phylogeny of Coronaviruses in Wild Birds from the Bering Strait Area (Beringia)
title Prevalence and Phylogeny of Coronaviruses in Wild Birds from the Bering Strait Area (Beringia)
title_full Prevalence and Phylogeny of Coronaviruses in Wild Birds from the Bering Strait Area (Beringia)
title_fullStr Prevalence and Phylogeny of Coronaviruses in Wild Birds from the Bering Strait Area (Beringia)
title_full_unstemmed Prevalence and Phylogeny of Coronaviruses in Wild Birds from the Bering Strait Area (Beringia)
title_short Prevalence and Phylogeny of Coronaviruses in Wild Birds from the Bering Strait Area (Beringia)
title_sort prevalence and phylogeny of coronaviruses in wild birds from the bering strait area (beringia)
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966397/
https://www.ncbi.nlm.nih.gov/pubmed/21060827
http://dx.doi.org/10.1371/journal.pone.0013640
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