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Frequent and Distinct Aberrations of DNA Methylation Patterns in Fibrolamellar Carcinoma of the Liver

BACKGROUND: Gene silencing due to aberrant DNA methylation is a frequent event in hepatocellular carcinoma (HCC) and also in hepatocellular adenoma (HCA). However, very little is known about epigenetic defects in fibrolamellar carcinoma (FLC), a rare variant of hepatocellular carcinoma that displays...

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Detalles Bibliográficos
Autores principales:	Tränkenschuh, Wolfgang, Puls, Florian, Christgen, Matthias, Albat, Cord, Heim, Albert, Poczkaj, Jeanette, Fleming, Peer, Kreipe, Hans, Lehmann, Ulrich
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966398/ https://www.ncbi.nlm.nih.gov/pubmed/21060828 http://dx.doi.org/10.1371/journal.pone.0013688

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