Wild Type and Mutant 2009 Pandemic Influenza A (H1N1) Viruses Cause More Severe Disease and Higher Mortality in Pregnant BALB/c Mice

BACKGROUND: Pregnant women infected by the pandemic influenza A (H1N1) 2009 virus had more severe disease and higher mortality but its pathogenesis is still unclear. PRINCIPAL FINDINGS: We showed that higher mortality, more severe pneumonitis, higher pulmonary viral load, lower peripheral blood T ly...

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Detalles Bibliográficos
Autores principales: Chan, Kwok-Hung, Zhang, Anna J. X., To, Kelvin K. W., Chan, Chris C. S., Poon, Vincent K. M., Guo, Kunyuan, Ng, Fai, Zhang, Qi-Wei, Leung, Virtual H. C., Cheung, Annie N. Y., Lau, Candy C. Y., Woo, Patrick C. Y., Tse, Herman, Wu, Wailan, Chen, Honglin, Zheng, Bo-Jian, Yuen, Kwok-Yung
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966430/
https://www.ncbi.nlm.nih.gov/pubmed/21060798
http://dx.doi.org/10.1371/journal.pone.0013757

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