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IL28B SNP rs8099917 Is Strongly Associated with Pegylated Interferon-α and Ribavirin Therapy Treatment Failure in HCV/HIV-1 Coinfected Patients

Recent genome-wide association studies report that the SNP rs8099917, located 8.9 kb upstream of the start codon of IL28B, is associated with both disease chronicity and therapeutic response to pegIFN-α and RBV in patients infected with genotype 1 HCV. To determine the effect of rs8099917 variation...

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Detalles Bibliográficos
Autores principales:	Aparicio, Ester, Parera, Mariona, Franco, Sandra, Pérez-Alvarez, Nuria, Tural, Cristina, Clotet, Bonaventura, Martínez, Miguel Angel
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966433/ https://www.ncbi.nlm.nih.gov/pubmed/21048934 http://dx.doi.org/10.1371/journal.pone.0013771

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