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Enzastaurin inhibits invasion and metastasis in lung cancer by diverse molecules

BACKGROUND: Enzastaurin (Enz) is a serine/threonine kinase inhibitor blocking protein kinase C (PKC)β/AKT pathway. However, an ability of this compound to inhibit cancer invasion and metastasis is not yet clearly elucidated. METHODS: The ability of Enz to inhibit invasion and metastasis, and to targ...

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Detalles Bibliográficos
Autores principales:	Körner, A, Mudduluru, G, Manegold, C, Allgayer, H
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966618/ https://www.ncbi.nlm.nih.gov/pubmed/20736951 http://dx.doi.org/10.1038/sj.bjc.6605818

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