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Loss of tumoral expression of soluble IL-6 receptor is associated with disease progression in colorectal cancer

BACKGROUND: Interleukin-6 (IL-6) binds both the membrane and soluble forms of the IL-6 receptor (sIL-6R), which induces a complex with gp130, and proliferation of tumour cells. The aim of this study is to clarify the relationship between tumoral sIL-6R expression and disease progression in colorecta...

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Detalles Bibliográficos
Autores principales:	Okugawa, Y, Miki, C, Toiyama, Y, Yasuda, H, Yokoe, T, Saigusa, S, Hiro, J, Tanaka, K, Inoue, Y, Kusunoki, M
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966622/ https://www.ncbi.nlm.nih.gov/pubmed/20823887 http://dx.doi.org/10.1038/sj.bjc.6605827

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