Neoadjuvant endocrine therapy in primary breast cancer: indications and use as a research tool

Neoadjuvant endocrine therapy has been increasingly employed in clinical practice to improve surgical options for postmenopausal women with bulky hormone receptor-positive breast cancer. Recent studies indicate that tumour response in this setting may predict long-term outcome of patients on adjuvan...

Descripción completa

Detalles Bibliográficos
Autores principales: Chia, Y H, Ellis, M J, Ma, C X
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966629/
https://www.ncbi.nlm.nih.gov/pubmed/20700118
http://dx.doi.org/10.1038/sj.bjc.6605845
_version_ 1782189607532625920
author Chia, Y H
Ellis, M J
Ma, C X
author_facet Chia, Y H
Ellis, M J
Ma, C X
author_sort Chia, Y H
collection PubMed
description Neoadjuvant endocrine therapy has been increasingly employed in clinical practice to improve surgical options for postmenopausal women with bulky hormone receptor-positive breast cancer. Recent studies indicate that tumour response in this setting may predict long-term outcome of patients on adjuvant endocrine therapy, which argues for its broader application in treating hormone receptor-positive disease. From the research perspective, neoadjuvant endocrine therapy provides a unique opportunity for studies of endocrine responsiveness and the development of novel therapeutic agents.
format Text
id pubmed-2966629
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-29666292011-09-07 Neoadjuvant endocrine therapy in primary breast cancer: indications and use as a research tool Chia, Y H Ellis, M J Ma, C X Br J Cancer Minireview Neoadjuvant endocrine therapy has been increasingly employed in clinical practice to improve surgical options for postmenopausal women with bulky hormone receptor-positive breast cancer. Recent studies indicate that tumour response in this setting may predict long-term outcome of patients on adjuvant endocrine therapy, which argues for its broader application in treating hormone receptor-positive disease. From the research perspective, neoadjuvant endocrine therapy provides a unique opportunity for studies of endocrine responsiveness and the development of novel therapeutic agents. Nature Publishing Group 2010-09-07 2010-08-10 /pmc/articles/PMC2966629/ /pubmed/20700118 http://dx.doi.org/10.1038/sj.bjc.6605845 Text en Copyright © 2010 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Minireview
Chia, Y H
Ellis, M J
Ma, C X
Neoadjuvant endocrine therapy in primary breast cancer: indications and use as a research tool
title Neoadjuvant endocrine therapy in primary breast cancer: indications and use as a research tool
title_full Neoadjuvant endocrine therapy in primary breast cancer: indications and use as a research tool
title_fullStr Neoadjuvant endocrine therapy in primary breast cancer: indications and use as a research tool
title_full_unstemmed Neoadjuvant endocrine therapy in primary breast cancer: indications and use as a research tool
title_short Neoadjuvant endocrine therapy in primary breast cancer: indications and use as a research tool
title_sort neoadjuvant endocrine therapy in primary breast cancer: indications and use as a research tool
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966629/
https://www.ncbi.nlm.nih.gov/pubmed/20700118
http://dx.doi.org/10.1038/sj.bjc.6605845
work_keys_str_mv AT chiayh neoadjuvantendocrinetherapyinprimarybreastcancerindicationsanduseasaresearchtool
AT ellismj neoadjuvantendocrinetherapyinprimarybreastcancerindicationsanduseasaresearchtool
AT macx neoadjuvantendocrinetherapyinprimarybreastcancerindicationsanduseasaresearchtool

Ejemplares similares