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Adjuvant chemoradiotherapy of advanced resectable rectal cancer: results of a randomised trial comparing modulation of 5-fluorouracil with folinic acid or with interferon-α

BACKGROUND: Standard adjuvant chemoradiotherapy of rectal cancer still consists of 5-fluorouracil (5-FU) only. Its cytotoxicity is enhanced by folinic acid (FA) and interferon-α (INFα). In this trial, the effects of FA and IFNα on adjuvant 5-FU chemoradiotherapy in locally advanced rectal cancer wer...

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Detalles Bibliográficos
Autores principales:	Kornmann, M, Staib, L, Wiegel, T, Kreuser, E-D, Kron, M, Baumann, W, Henne-Bruns, D, Link, K-H
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967051/ https://www.ncbi.nlm.nih.gov/pubmed/20877353 http://dx.doi.org/10.1038/sj.bjc.6605871

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