Carcinoma in situ testis displays permissive chromatin modifications similar to immature foetal germ cells

BACKGROUND: The majority of testicular germ cell cancers develop through a pre-invasive carcinoma in situ (CIS) stage. The CIS cell is a neoplastic counterpart of foetal germ cells. During their development, foetal germ cells undergo extensive and essential epigenetic modifications, but little is kn...

Descripción completa

Detalles Bibliográficos
Autores principales: Almstrup, K, Nielsen, J E, Mlynarska, O, Jansen, M T, Jørgensen, A, Skakkebæk, N E, Rajpert-De Meyts, E
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967056/
https://www.ncbi.nlm.nih.gov/pubmed/20823885
http://dx.doi.org/10.1038/sj.bjc.6605880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967056/
https://www.ncbi.nlm.nih.gov/pubmed/20823885
http://dx.doi.org/10.1038/sj.bjc.6605880

Ejemplares similares