Inhibition of Id proteins by a peptide aptamer induces cell-cycle arrest and apoptosis in ovarian cancer cells

BACKGROUND: Inhibitors of DNA-binding proteins (Id1-4), lacking the basic DNA-binding domain, function as dominant inhibitors of cell-cycle regulators. Overexpression of Id proteins promotes cancer cell proliferation and resistance against apoptosis. Level of Id protein expression, especially of Id1...

Descripción completa

Detalles Bibliográficos
Autores principales: Mern, D S, Hasskarl, J, Burwinkel, B
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967066/
https://www.ncbi.nlm.nih.gov/pubmed/20842131
http://dx.doi.org/10.1038/sj.bjc.6605897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967066/
https://www.ncbi.nlm.nih.gov/pubmed/20842131
http://dx.doi.org/10.1038/sj.bjc.6605897

Ejemplares similares