MicroRNA in lung cancer

MicroRNAs (miRNAs) are small non-protein-coding RNAs that function as endogenous negative gene regulators. Dysfunctions of miRNAs are frequently found in malignancies, including lung cancer. In this review, we summarise the current understanding of miRNAs in lung cancer tumourigenesis, and highlight...

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Detalles Bibliográficos
Autores principales: Lin, P-Y, Yu, S-L, Yang, P-C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967070/
https://www.ncbi.nlm.nih.gov/pubmed/20859290
http://dx.doi.org/10.1038/sj.bjc.6605901
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author Lin, P-Y
Yu, S-L
Yang, P-C
author_facet Lin, P-Y
Yu, S-L
Yang, P-C
author_sort Lin, P-Y
collection PubMed
description MicroRNAs (miRNAs) are small non-protein-coding RNAs that function as endogenous negative gene regulators. Dysfunctions of miRNAs are frequently found in malignancies, including lung cancer. In this review, we summarise the current understanding of miRNAs in lung cancer tumourigenesis, and highlight their potential in overcoming drug resistance, abetting histological sub-classification techniques, and serving as biomarkers for lung cancer risk stratification and outcome prediction.
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spelling pubmed-29670702011-10-12 MicroRNA in lung cancer Lin, P-Y Yu, S-L Yang, P-C Br J Cancer Minireview MicroRNAs (miRNAs) are small non-protein-coding RNAs that function as endogenous negative gene regulators. Dysfunctions of miRNAs are frequently found in malignancies, including lung cancer. In this review, we summarise the current understanding of miRNAs in lung cancer tumourigenesis, and highlight their potential in overcoming drug resistance, abetting histological sub-classification techniques, and serving as biomarkers for lung cancer risk stratification and outcome prediction. Nature Publishing Group 2010-10-12 2010-09-21 /pmc/articles/PMC2967070/ /pubmed/20859290 http://dx.doi.org/10.1038/sj.bjc.6605901 Text en Copyright © 2010 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Minireview
Lin, P-Y
Yu, S-L
Yang, P-C
MicroRNA in lung cancer
title MicroRNA in lung cancer
title_full MicroRNA in lung cancer
title_fullStr MicroRNA in lung cancer
title_full_unstemmed MicroRNA in lung cancer
title_short MicroRNA in lung cancer
title_sort microrna in lung cancer
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967070/
https://www.ncbi.nlm.nih.gov/pubmed/20859290
http://dx.doi.org/10.1038/sj.bjc.6605901
work_keys_str_mv AT linpy micrornainlungcancer
AT yusl micrornainlungcancer
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