OBSESSIVE - COMPULSIVE SYMPTOMS DURING CLOZAPINE TREATMENT

Development of obsessive-compulsive symptoms during clozapine treatment in schizophrenics has been noted in few reports from west. In our cases, three schizophrenic patients resistant to typical antipsychotics developed obsessive-compulsive symptoms during clozapine treatment. Since clozapine is a p...

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Detalles Bibliográficos
Autores principales: Agarwal, A.K., Khalid, Abdul
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 1997
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967125/
https://www.ncbi.nlm.nih.gov/pubmed/21584085
Descripción
Sumario:Development of obsessive-compulsive symptoms during clozapine treatment in schizophrenics has been noted in few reports from west. In our cases, three schizophrenic patients resistant to typical antipsychotics developed obsessive-compulsive symptoms during clozapine treatment. Since clozapine is a potent 5-HT(2) receptor blocker, role of serotonergic systems in the development of obsessive-compulsive symptoms may be considered. It may be prudent to be vigilant for the emergence of obsessive-compulsive symptoms in all patients treated with clozapine.

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