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Synergistic epigenetic reactivation of estrogen receptor-α (ERα) by combined green tea polyphenol and histone deacetylase inhibitor in ERα-negative breast cancer cells

BACKGROUND: The status of estrogen receptor-α (ERα) is critical to the clinical prognosis and therapeutic approach in breast cancer. ERα-negative breast cancer is clinically aggressive and has a poor prognosis because of the lack of hormone target-directed therapies. Previous studies have shown that...

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Detalles Bibliográficos
Autores principales:	Li, Yuanyuan, Yuan, Yih-Ying, Meeran, Syed M, Tollefsbol, Trygve O
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967543/ https://www.ncbi.nlm.nih.gov/pubmed/20946668 http://dx.doi.org/10.1186/1476-4598-9-274

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