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Peroxynitrite Mediates Diabetes-Induced Endothelial Dysfunction: Possible Role of Rho Kinase Activation
Endothelial dysfunction is characterized by reduced bioavailability of NO due to its inactivation to form peroxynitrite or reduced expression of eNOS. Here, we examine the causal role of peroxynitrite in mediating diabetes-induced endothelial dysfunction. Diabetes was induced by STZ-injection, and r...
Autores principales: | El-Remessy, Azza B., Tawfik, Huda E., Matragoon, Suraporn, Pillai, Bindu, Caldwell, Ruth B., Caldwell, R. William |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967829/ https://www.ncbi.nlm.nih.gov/pubmed/21052489 http://dx.doi.org/10.1155/2010/247861 |
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