(Z)-5-Fluoro-3-[(1H-pyrrol-2-yl)methyl­ene]indolin-2-one

The title compound, C(13)H(9)FN(2)O, a potential neuroprotective agent, consists of an indolinone and a pyrrolyl unit [dihedral angle between the ring planes = 4.9 (1)°]. An intra­molecular hydrogen bond between the carbonyl O atom and the NH group of pyrrole correlates with the Z arrangement of the...

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Detalles Bibliográficos
Autores principales: Zhang, Hongming, Ankati, Haribabu, Akubathini, Shashidhar Kumar, Biehl, Ed
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967860/
https://www.ncbi.nlm.nih.gov/pubmed/21581718
http://dx.doi.org/10.1107/S1600536808040178
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author Zhang, Hongming
Ankati, Haribabu
Akubathini, Shashidhar Kumar
Biehl, Ed
author_facet Zhang, Hongming
Ankati, Haribabu
Akubathini, Shashidhar Kumar
Biehl, Ed
author_sort Zhang, Hongming
collection PubMed
description The title compound, C(13)H(9)FN(2)O, a potential neuroprotective agent, consists of an indolinone and a pyrrolyl unit [dihedral angle between the ring planes = 4.9 (1)°]. An intra­molecular hydrogen bond between the carbonyl O atom and the NH group of pyrrole correlates with the Z arrangement of the substituents at the C=C bond. In the crystal, inversion dimers occur, linked by pairs of N—H⋯O bonds.
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spelling pubmed-29678602010-12-30 (Z)-5-Fluoro-3-[(1H-pyrrol-2-yl)methyl­ene]indolin-2-one Zhang, Hongming Ankati, Haribabu Akubathini, Shashidhar Kumar Biehl, Ed Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(13)H(9)FN(2)O, a potential neuroprotective agent, consists of an indolinone and a pyrrolyl unit [dihedral angle between the ring planes = 4.9 (1)°]. An intra­molecular hydrogen bond between the carbonyl O atom and the NH group of pyrrole correlates with the Z arrangement of the substituents at the C=C bond. In the crystal, inversion dimers occur, linked by pairs of N—H⋯O bonds. International Union of Crystallography 2008-12-03 /pmc/articles/PMC2967860/ /pubmed/21581718 http://dx.doi.org/10.1107/S1600536808040178 Text en © Zhang et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Zhang, Hongming
Ankati, Haribabu
Akubathini, Shashidhar Kumar
Biehl, Ed
(Z)-5-Fluoro-3-[(1H-pyrrol-2-yl)methyl­ene]indolin-2-one
title (Z)-5-Fluoro-3-[(1H-pyrrol-2-yl)methyl­ene]indolin-2-one
title_full (Z)-5-Fluoro-3-[(1H-pyrrol-2-yl)methyl­ene]indolin-2-one
title_fullStr (Z)-5-Fluoro-3-[(1H-pyrrol-2-yl)methyl­ene]indolin-2-one
title_full_unstemmed (Z)-5-Fluoro-3-[(1H-pyrrol-2-yl)methyl­ene]indolin-2-one
title_short (Z)-5-Fluoro-3-[(1H-pyrrol-2-yl)methyl­ene]indolin-2-one
title_sort (z)-5-fluoro-3-[(1h-pyrrol-2-yl)methyl­ene]indolin-2-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967860/
https://www.ncbi.nlm.nih.gov/pubmed/21581718
http://dx.doi.org/10.1107/S1600536808040178
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AT akubathinishashidharkumar z5fluoro31hpyrrol2ylmethyleneindolin2one
AT biehled z5fluoro31hpyrrol2ylmethyleneindolin2one

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