4-Chloro-2-((1R)-1-{[(R)-(2-chlorophen­yl)(cyclo­pent­yl)meth­yl]amino}prop­yl)phenol

In the title compound, C(21)H(25)Cl(2)NO, the dihedral angle between the two benzene rings is 33.18 (11)°. The five-membered ring adopts an envelope conformation. There is an intra­molecular O—H⋯N hydrogen bond. In the crystal, mol­ecules are linked by weak N—H⋯Cl hydrogen bonds, forming a helical c...

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Detalles Bibliográficos
Autores principales: Zhang, Guang-You, Yang, Ting, Xu, Bao-Wang, Chen, Di-Juan, Wang, Wan-Hui
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2008
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2968043/
https://www.ncbi.nlm.nih.gov/pubmed/21581584
http://dx.doi.org/10.1107/S1600536808042025
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author Zhang, Guang-You
Yang, Ting
Xu, Bao-Wang
Chen, Di-Juan
Wang, Wan-Hui
author_facet Zhang, Guang-You
Yang, Ting
Xu, Bao-Wang
Chen, Di-Juan
Wang, Wan-Hui
author_sort Zhang, Guang-You
collection PubMed
description In the title compound, C(21)H(25)Cl(2)NO, the dihedral angle between the two benzene rings is 33.18 (11)°. The five-membered ring adopts an envelope conformation. There is an intra­molecular O—H⋯N hydrogen bond. In the crystal, mol­ecules are linked by weak N—H⋯Cl hydrogen bonds, forming a helical chain along the c axis.
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spelling pubmed-29680432010-12-30 4-Chloro-2-((1R)-1-{[(R)-(2-chlorophen­yl)(cyclo­pent­yl)meth­yl]amino}prop­yl)phenol Zhang, Guang-You Yang, Ting Xu, Bao-Wang Chen, Di-Juan Wang, Wan-Hui Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(21)H(25)Cl(2)NO, the dihedral angle between the two benzene rings is 33.18 (11)°. The five-membered ring adopts an envelope conformation. There is an intra­molecular O—H⋯N hydrogen bond. In the crystal, mol­ecules are linked by weak N—H⋯Cl hydrogen bonds, forming a helical chain along the c axis. International Union of Crystallography 2008-12-13 /pmc/articles/PMC2968043/ /pubmed/21581584 http://dx.doi.org/10.1107/S1600536808042025 Text en © Zhang et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Zhang, Guang-You
Yang, Ting
Xu, Bao-Wang
Chen, Di-Juan
Wang, Wan-Hui
4-Chloro-2-((1R)-1-{[(R)-(2-chlorophen­yl)(cyclo­pent­yl)meth­yl]amino}prop­yl)phenol
title 4-Chloro-2-((1R)-1-{[(R)-(2-chlorophen­yl)(cyclo­pent­yl)meth­yl]amino}prop­yl)phenol
title_full 4-Chloro-2-((1R)-1-{[(R)-(2-chlorophen­yl)(cyclo­pent­yl)meth­yl]amino}prop­yl)phenol
title_fullStr 4-Chloro-2-((1R)-1-{[(R)-(2-chlorophen­yl)(cyclo­pent­yl)meth­yl]amino}prop­yl)phenol
title_full_unstemmed 4-Chloro-2-((1R)-1-{[(R)-(2-chlorophen­yl)(cyclo­pent­yl)meth­yl]amino}prop­yl)phenol
title_short 4-Chloro-2-((1R)-1-{[(R)-(2-chlorophen­yl)(cyclo­pent­yl)meth­yl]amino}prop­yl)phenol
title_sort 4-chloro-2-((1r)-1-{[(r)-(2-chlorophen­yl)(cyclo­pent­yl)meth­yl]amino}prop­yl)phenol
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2968043/
https://www.ncbi.nlm.nih.gov/pubmed/21581584
http://dx.doi.org/10.1107/S1600536808042025
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