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Cell Cycle Deregulation in Ewing's Sarcoma Pathogenesis

Ewing's sarcoma is a highly aggressive pediatric tumor of bone that usually contains the characteristic chromosomal translocation t(11;22)(q24;q12). This translocation encodes the oncogenic fusion protein EWS/FLI, which acts as an aberrant transcription factor to deregulate target genes necessa...

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Detalles Bibliográficos
Autores principales:	Kowalewski, Ashley A., Randall, R. Lor, Lessnick, Stephen L.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2011
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2968116/ https://www.ncbi.nlm.nih.gov/pubmed/21052502 http://dx.doi.org/10.1155/2011/598704

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