rac-(4R,17S,18R,26R)-Ethyl 4′-methoxy­carbonyl-5′′-(4-methoxy­phen­yl)-1′-methyl-2,3′′-dioxo-2′′,3′′-dihydro­indoline-3-spiro-2′-pyrrolidine-3′-spiro-2′′-thia­zolo[3,2-a]pyrimidine-6′′-carboxyl­ate

In the title compound, C(30)H(30)N(4)O(7)S, the two spiro junctions link a planar 2-oxindole ring [with a mean deviation from the plane of 0.0319 (3) Å, a pyrrolidine ring in an envelope conformation and a thia­zolo[3,2-a]pyrimidine system. Two mol­ecules are connected into a dimer by two N—H⋯O hydr...

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Detalles Bibliográficos
Autores principales: Hou, Zhao-Hui, Zhou, Ning-Bo, He, Bin-Hong, Li, Xiao-Fang
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2968168/
https://www.ncbi.nlm.nih.gov/pubmed/21581991
http://dx.doi.org/10.1107/S160053680900261X
Descripción
Sumario:In the title compound, C(30)H(30)N(4)O(7)S, the two spiro junctions link a planar 2-oxindole ring [with a mean deviation from the plane of 0.0319 (3) Å, a pyrrolidine ring in an envelope conformation and a thia­zolo[3,2-a]pyrimidine system. Two mol­ecules are connected into a dimer by two N—H⋯O hydrogen bonds, forming an R (2) (2)(8) graph-set motif. The title compound has four stereogenic centers and appears as a racemic mixture of one single diastereoisomer (RSRR/SRSS).

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