1′,3′,3′-Trimethyl-2,3-diphenyl-2,3-di­hydro­isoxazole-5(4H)-spiro-2′-indoline

Two diastereoisomers of the title compound, C(25)H(26)N(2)O, have been prepared by cyclo­addition between 1,3,3-trimethyl-2-methyl­eneindoline and C-phenyl-N-phenyl­nitrone. The stereochemistry of the major diastereoisomer, viz. S,R/R,S, is confirmed by the X-ray analysis. The oxazole and the pyrole...

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Autores principales: Laghrib, Naoual, Daran, Jean-Claude, Fihi, Rachid, Majidi, Lhou, Azrour, Mohamed
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2968171/
https://www.ncbi.nlm.nih.gov/pubmed/21581972
http://dx.doi.org/10.1107/S1600536809002062
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author Laghrib, Naoual
Daran, Jean-Claude
Fihi, Rachid
Majidi, Lhou
Azrour, Mohamed
author_facet Laghrib, Naoual
Daran, Jean-Claude
Fihi, Rachid
Majidi, Lhou
Azrour, Mohamed
author_sort Laghrib, Naoual
collection PubMed
description Two diastereoisomers of the title compound, C(25)H(26)N(2)O, have been prepared by cyclo­addition between 1,3,3-trimethyl-2-methyl­eneindoline and C-phenyl-N-phenyl­nitrone. The stereochemistry of the major diastereoisomer, viz. S,R/R,S, is confirmed by the X-ray analysis. The oxazole and the pyrole rings have envelope conformations. The packing is stabilized by weak C—H⋯π inter­actions involving the phenyl ring attached to the N atom of the oxazole and the phenyl ring of the indole fragment.
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spelling pubmed-29681712010-12-30 1′,3′,3′-Trimethyl-2,3-diphenyl-2,3-di­hydro­isoxazole-5(4H)-spiro-2′-indoline Laghrib, Naoual Daran, Jean-Claude Fihi, Rachid Majidi, Lhou Azrour, Mohamed Acta Crystallogr Sect E Struct Rep Online Organic Papers Two diastereoisomers of the title compound, C(25)H(26)N(2)O, have been prepared by cyclo­addition between 1,3,3-trimethyl-2-methyl­eneindoline and C-phenyl-N-phenyl­nitrone. The stereochemistry of the major diastereoisomer, viz. S,R/R,S, is confirmed by the X-ray analysis. The oxazole and the pyrole rings have envelope conformations. The packing is stabilized by weak C—H⋯π inter­actions involving the phenyl ring attached to the N atom of the oxazole and the phenyl ring of the indole fragment. International Union of Crystallography 2009-01-23 /pmc/articles/PMC2968171/ /pubmed/21581972 http://dx.doi.org/10.1107/S1600536809002062 Text en © Laghrib et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Laghrib, Naoual
Daran, Jean-Claude
Fihi, Rachid
Majidi, Lhou
Azrour, Mohamed
1′,3′,3′-Trimethyl-2,3-diphenyl-2,3-di­hydro­isoxazole-5(4H)-spiro-2′-indoline
title 1′,3′,3′-Trimethyl-2,3-diphenyl-2,3-di­hydro­isoxazole-5(4H)-spiro-2′-indoline
title_full 1′,3′,3′-Trimethyl-2,3-diphenyl-2,3-di­hydro­isoxazole-5(4H)-spiro-2′-indoline
title_fullStr 1′,3′,3′-Trimethyl-2,3-diphenyl-2,3-di­hydro­isoxazole-5(4H)-spiro-2′-indoline
title_full_unstemmed 1′,3′,3′-Trimethyl-2,3-diphenyl-2,3-di­hydro­isoxazole-5(4H)-spiro-2′-indoline
title_short 1′,3′,3′-Trimethyl-2,3-diphenyl-2,3-di­hydro­isoxazole-5(4H)-spiro-2′-indoline
title_sort 1′,3′,3′-trimethyl-2,3-diphenyl-2,3-di­hydro­isoxazole-5(4h)-spiro-2′-indoline
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2968171/
https://www.ncbi.nlm.nih.gov/pubmed/21581972
http://dx.doi.org/10.1107/S1600536809002062
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AT azrourmohamed 133trimethyl23diphenyl23dihydroisoxazole54hspiro2indoline

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