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3-{1-[4-(2-Methyl­prop­yl)phen­yl]eth­yl}-1-(morpholinometh­yl)-4-(4-nitro­benzyl­ideneamino)-1H-1,2,4-triazole-5(4H)-thione

The title ibuprofen-containing Mannich derivative, C(26)H(32)N(6)O(3)S, crystallizes with two independent mol­ecules in the asymmetric unit. The morpholine ring in each mol­ecule adopts a chair conformation. The 1,2,4-triazole ring forms dihedral angles of 2.13 (10) and 75.52 (10)° with the two subs...

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Detalles Bibliográficos
Autores principales: Fun, Hoong-Kun, Chantrapromma, Suchada, Sujith, K. V., Kalluraya, B.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2968455/
https://www.ncbi.nlm.nih.gov/pubmed/21582161
http://dx.doi.org/10.1107/S1600536809003870
Descripción
Sumario:The title ibuprofen-containing Mannich derivative, C(26)H(32)N(6)O(3)S, crystallizes with two independent mol­ecules in the asymmetric unit. The morpholine ring in each mol­ecule adopts a chair conformation. The 1,2,4-triazole ring forms dihedral angles of 2.13 (10) and 75.52 (10)° with the two substituted benzene rings in one mol­ecule, with corresponding values of 19.36 (11)° and 89.03 (10)° in the other. The nitro groups are twisted from the attached benzene ring in each mol­ecule. In the crystal packing, mol­ecules are linked into supra­molecular chains via weak C—H⋯O, C—H⋯N and C—H⋯S inter­actions, and C—H⋯π and N—O⋯π links also occur.