Cargando…

N-(2,3-Dimethyl­phen­yl)-4-hydr­oxy-2-methyl-2H-1,2-benzothia­zine-3-carboxamide 1,1-dioxide

In the crystal structure of the title compound, C(18)H(18)N(2)O(4)S, the thia­zine ring adopts a distorted half-chair conformation. 1,2-Benzothia­zines of this kind have a wide range of biological activities and are mainly used as medicines in the treatment of inflammation and rheumatoid arthritis....

Descripción completa

Detalles Bibliográficos
Autores principales: Siddiqui, Waseeq Ahmad, Bukahari, Iftikhar Hussain, Zia-ur-Rehman, Muhammad, Khan, Islam Ullah, Tizzard, Graham John
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2968491/
https://www.ncbi.nlm.nih.gov/pubmed/21582293
http://dx.doi.org/10.1107/S1600536809006837
Descripción
Sumario:In the crystal structure of the title compound, C(18)H(18)N(2)O(4)S, the thia­zine ring adopts a distorted half-chair conformation. 1,2-Benzothia­zines of this kind have a wide range of biological activities and are mainly used as medicines in the treatment of inflammation and rheumatoid arthritis. The enolic H atom is involved in an intra­molecular O—H⋯O hydrogen bond, forming a six-membered ring. The mol­ecules arrange themselves into centrosymmetric dimers by means of inter­molecular N—H⋯O hydrogen bonds. A weak inter­molcular C—H⋯O inter­action is also present.