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N-(2,3-Dimethylphenyl)-4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
In the crystal structure of the title compound, C(18)H(18)N(2)O(4)S, the thiazine ring adopts a distorted half-chair conformation. 1,2-Benzothiazines of this kind have a wide range of biological activities and are mainly used as medicines in the treatment of inflammation and rheumatoid arthritis....
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2968491/ https://www.ncbi.nlm.nih.gov/pubmed/21582293 http://dx.doi.org/10.1107/S1600536809006837 |
Sumario: | In the crystal structure of the title compound, C(18)H(18)N(2)O(4)S, the thiazine ring adopts a distorted half-chair conformation. 1,2-Benzothiazines of this kind have a wide range of biological activities and are mainly used as medicines in the treatment of inflammation and rheumatoid arthritis. The enolic H atom is involved in an intramolecular O—H⋯O hydrogen bond, forming a six-membered ring. The molecules arrange themselves into centrosymmetric dimers by means of intermolecular N—H⋯O hydrogen bonds. A weak intermolcular C—H⋯O interaction is also present. |
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