2-(4-Fluoro­anilino)-3-(2-hydroxy­ethyl)quinazolin-4(3H)-one

The mol­ecular and crystal structures of the title compound, C(16)H(14)FN(3)O(2), are stabilized by intra­molecular N—H⋯O and inter­molecular O—H⋯O hydrogen bonds. The existence of non-classical intra­molecular C—H⋯N hydrogen bonds provides a dihedral angle between the fluoro-substituted benzene and...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Jiao, Yuan-Hong, Liu, Bin, Chen, Xue-Mei, Ruan, Min, Xu, Ling-Hua
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2968625/
https://www.ncbi.nlm.nih.gov/pubmed/21582287
http://dx.doi.org/10.1107/S1600536809006254
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author Zhang, Qian
Jiao, Yuan-Hong
Liu, Bin
Chen, Xue-Mei
Ruan, Min
Xu, Ling-Hua
author_facet Zhang, Qian
Jiao, Yuan-Hong
Liu, Bin
Chen, Xue-Mei
Ruan, Min
Xu, Ling-Hua
author_sort Zhang, Qian
collection PubMed
description The mol­ecular and crystal structures of the title compound, C(16)H(14)FN(3)O(2), are stabilized by intra­molecular N—H⋯O and inter­molecular O—H⋯O hydrogen bonds. The existence of non-classical intra­molecular C—H⋯N hydrogen bonds provides a dihedral angle between the fluoro-substituted benzene and pyrimidinone rings of 7.9 (1)°.
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spelling pubmed-29686252010-12-30 2-(4-Fluoro­anilino)-3-(2-hydroxy­ethyl)quinazolin-4(3H)-one Zhang, Qian Jiao, Yuan-Hong Liu, Bin Chen, Xue-Mei Ruan, Min Xu, Ling-Hua Acta Crystallogr Sect E Struct Rep Online Organic Papers The mol­ecular and crystal structures of the title compound, C(16)H(14)FN(3)O(2), are stabilized by intra­molecular N—H⋯O and inter­molecular O—H⋯O hydrogen bonds. The existence of non-classical intra­molecular C—H⋯N hydrogen bonds provides a dihedral angle between the fluoro-substituted benzene and pyrimidinone rings of 7.9 (1)°. International Union of Crystallography 2009-02-28 /pmc/articles/PMC2968625/ /pubmed/21582287 http://dx.doi.org/10.1107/S1600536809006254 Text en © Zhang et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Zhang, Qian
Jiao, Yuan-Hong
Liu, Bin
Chen, Xue-Mei
Ruan, Min
Xu, Ling-Hua
2-(4-Fluoro­anilino)-3-(2-hydroxy­ethyl)quinazolin-4(3H)-one
title 2-(4-Fluoro­anilino)-3-(2-hydroxy­ethyl)quinazolin-4(3H)-one
title_full 2-(4-Fluoro­anilino)-3-(2-hydroxy­ethyl)quinazolin-4(3H)-one
title_fullStr 2-(4-Fluoro­anilino)-3-(2-hydroxy­ethyl)quinazolin-4(3H)-one
title_full_unstemmed 2-(4-Fluoro­anilino)-3-(2-hydroxy­ethyl)quinazolin-4(3H)-one
title_short 2-(4-Fluoro­anilino)-3-(2-hydroxy­ethyl)quinazolin-4(3H)-one
title_sort 2-(4-fluoro­anilino)-3-(2-hydroxy­ethyl)quinazolin-4(3h)-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2968625/
https://www.ncbi.nlm.nih.gov/pubmed/21582287
http://dx.doi.org/10.1107/S1600536809006254
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