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Effect of Nanoparticle Conjugation on Gene Silencing by RNA Interference

[Image: see text] RNA interference (RNAi) is a cellular process whereby the silencing of a particular gene is mediated by short RNAs (siRNAs). Although siRNAs have great therapeutic potential, cellular delivery has been a challenge. Nanoparticle-siRNA conjugates have emerged as potential delivery ve...

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Detalles Bibliográficos
Autores principales: Singh, Neetu, Agrawal, Amit, Leung, Anthony K. L., Sharp, Phillip A., Bhatia, Sangeeta N.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2968757/
https://www.ncbi.nlm.nih.gov/pubmed/20518524
http://dx.doi.org/10.1021/ja102132e