4-(3-Methoxy­phen­oxy)butyric acid

In the title compound, C(11)H(14)O(4), an inter­mediate for the synthesis of a new kind of estrogen receptor modulator, all non-H atoms lie on a common plane (r.m.s. deviation = 0.0472 Å). All C—C bonds in the side chain are in a trans conformation, and the hydroxyl group is also trans to the methyl...

Descripción completa

Detalles Bibliográficos
Autores principales: Heilmann-Brohl, Julia, Jaouen, Gérard, Bolte, Michael
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2968774/
https://www.ncbi.nlm.nih.gov/pubmed/21582503
http://dx.doi.org/10.1107/S1600536809008186
_version_ 1782189961967042560
author Heilmann-Brohl, Julia
Jaouen, Gérard
Bolte, Michael
author_facet Heilmann-Brohl, Julia
Jaouen, Gérard
Bolte, Michael
author_sort Heilmann-Brohl, Julia
collection PubMed
description In the title compound, C(11)H(14)O(4), an inter­mediate for the synthesis of a new kind of estrogen receptor modulator, all non-H atoms lie on a common plane (r.m.s. deviation = 0.0472 Å). All C—C bonds in the side chain are in a trans conformation, and the hydroxyl group is also trans to the methyl­ene chain. In the crystal structure, mol­ecules form centrosymmetric dimers showing a head-to-head arrangement which is stabilized by O—H⋯O hydrogen bonds. A weak C—H⋯O contact is also present.
format Text
id pubmed-2968774
institution National Center for Biotechnology Information
language English
publishDate 2009
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-29687742010-12-30 4-(3-Methoxy­phen­oxy)butyric acid Heilmann-Brohl, Julia Jaouen, Gérard Bolte, Michael Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(11)H(14)O(4), an inter­mediate for the synthesis of a new kind of estrogen receptor modulator, all non-H atoms lie on a common plane (r.m.s. deviation = 0.0472 Å). All C—C bonds in the side chain are in a trans conformation, and the hydroxyl group is also trans to the methyl­ene chain. In the crystal structure, mol­ecules form centrosymmetric dimers showing a head-to-head arrangement which is stabilized by O—H⋯O hydrogen bonds. A weak C—H⋯O contact is also present. International Union of Crystallography 2009-03-19 /pmc/articles/PMC2968774/ /pubmed/21582503 http://dx.doi.org/10.1107/S1600536809008186 Text en © Heilmann-Brohl et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Heilmann-Brohl, Julia
Jaouen, Gérard
Bolte, Michael
4-(3-Methoxy­phen­oxy)butyric acid
title 4-(3-Methoxy­phen­oxy)butyric acid
title_full 4-(3-Methoxy­phen­oxy)butyric acid
title_fullStr 4-(3-Methoxy­phen­oxy)butyric acid
title_full_unstemmed 4-(3-Methoxy­phen­oxy)butyric acid
title_short 4-(3-Methoxy­phen­oxy)butyric acid
title_sort 4-(3-methoxy­phen­oxy)butyric acid
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2968774/
https://www.ncbi.nlm.nih.gov/pubmed/21582503
http://dx.doi.org/10.1107/S1600536809008186
work_keys_str_mv AT heilmannbrohljulia 43methoxyphenoxybutyricacid
AT jaouengerard 43methoxyphenoxybutyricacid
AT boltemichael 43methoxyphenoxybutyricacid

Ejemplares similares