Di-tert-butyl N-[2,6-bis­(methoxy­meth­oxy)phen­yl]imino­diacetate

The title mol­ecule, C(20)H(31)NO(8), has pseudo-C2 symmetry about the C—N bond, with the bis­(tert-butoxy­carbon­yl)amino group twisted from the benzene ring plane by ca 60° and the bulky tert-butoxy­carbonyl (Boc) groups are orientated away from the substituted aniline group. As part of an anti­ba...

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Detalles Bibliográficos
Autores principales: Capuano, Ben, Crosby, Ian T., Forsyth, Craig M., Khakham, Yelena, Manallack, David T.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2968827/
https://www.ncbi.nlm.nih.gov/pubmed/21582540
http://dx.doi.org/10.1107/S1600536809009246
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author Capuano, Ben
Crosby, Ian T.
Forsyth, Craig M.
Khakham, Yelena
Manallack, David T.
author_facet Capuano, Ben
Crosby, Ian T.
Forsyth, Craig M.
Khakham, Yelena
Manallack, David T.
author_sort Capuano, Ben
collection PubMed
description The title mol­ecule, C(20)H(31)NO(8), has pseudo-C2 symmetry about the C—N bond, with the bis­(tert-butoxy­carbon­yl)amino group twisted from the benzene ring plane by ca 60° and the bulky tert-butoxy­carbonyl (Boc) groups are orientated away from the substituted aniline group. As part of an anti­bacterial drug discovery programme furnishing analogues of platensimycin, we unexpectedly synthesized the bis-Boc-protected aniline.
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spelling pubmed-29688272010-12-30 Di-tert-butyl N-[2,6-bis­(methoxy­meth­oxy)phen­yl]imino­diacetate Capuano, Ben Crosby, Ian T. Forsyth, Craig M. Khakham, Yelena Manallack, David T. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title mol­ecule, C(20)H(31)NO(8), has pseudo-C2 symmetry about the C—N bond, with the bis­(tert-butoxy­carbon­yl)amino group twisted from the benzene ring plane by ca 60° and the bulky tert-butoxy­carbonyl (Boc) groups are orientated away from the substituted aniline group. As part of an anti­bacterial drug discovery programme furnishing analogues of platensimycin, we unexpectedly synthesized the bis-Boc-protected aniline. International Union of Crystallography 2009-03-25 /pmc/articles/PMC2968827/ /pubmed/21582540 http://dx.doi.org/10.1107/S1600536809009246 Text en © Capuano et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Capuano, Ben
Crosby, Ian T.
Forsyth, Craig M.
Khakham, Yelena
Manallack, David T.
Di-tert-butyl N-[2,6-bis­(methoxy­meth­oxy)phen­yl]imino­diacetate
title Di-tert-butyl N-[2,6-bis­(methoxy­meth­oxy)phen­yl]imino­diacetate
title_full Di-tert-butyl N-[2,6-bis­(methoxy­meth­oxy)phen­yl]imino­diacetate
title_fullStr Di-tert-butyl N-[2,6-bis­(methoxy­meth­oxy)phen­yl]imino­diacetate
title_full_unstemmed Di-tert-butyl N-[2,6-bis­(methoxy­meth­oxy)phen­yl]imino­diacetate
title_short Di-tert-butyl N-[2,6-bis­(methoxy­meth­oxy)phen­yl]imino­diacetate
title_sort di-tert-butyl n-[2,6-bis­(methoxy­meth­oxy)phen­yl]imino­diacetate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2968827/
https://www.ncbi.nlm.nih.gov/pubmed/21582540
http://dx.doi.org/10.1107/S1600536809009246
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AT khakhamyelena ditertbutyln26bismethoxymethoxyphenyliminodiacetate
AT manallackdavidt ditertbutyln26bismethoxymethoxyphenyliminodiacetate

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