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(R)-4-[2-(Methylsulfanyl)pyrimidin-4-yl]-1-(tetrahydrofuran-3-yl)-1H-pyrazol-5-amine
The title compound, C(12)H(15)N(5)OS, was obtained by reaction of 2-(2-(methylthio)pyrimidin-4-yl)-3-oxopropanenitrile with (tetrahydrofuran-3-yl)hydrazine dihydrochloride, and the racemic product was subsequently separated by chiral chromatography (first peak; [α](D) (20) = +51.3°). The chiral...
Autores principales: | Liu, Zhengyu, Liu, Kevin K.-C., Elleraas, Jeff, Rheingold, Arnold L., DiPasquale, Antonio, Yanovsky, Alex |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2968870/ https://www.ncbi.nlm.nih.gov/pubmed/21582437 http://dx.doi.org/10.1107/S160053680900734X |
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