(9S,13R,14R)-7,8-Didehydro-3,4,7-trimeth­oxy-17-methyl­morphinan-6-one

The title compound, C(20)H(25)NO(4), was synthesized by a Mitsunobu reaction of sinomenine [(9S,13R,14R)-7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one] with methanol. The chiral centers were unchanged during the reaction. Intra­molecular C—H⋯O hydrogen bonds result in the formation...

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Detalles Bibliográficos
Autores principales: Li, Yu-Feng, Qian, Yi, Yin, Li-He, Lv, Ran, Zhu, Hong-Jun
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2969083/
https://www.ncbi.nlm.nih.gov/pubmed/21582431
http://dx.doi.org/10.1107/S1600536808040749
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author Li, Yu-Feng
Qian, Yi
Yin, Li-He
Lv, Ran
Zhu, Hong-Jun
author_facet Li, Yu-Feng
Qian, Yi
Yin, Li-He
Lv, Ran
Zhu, Hong-Jun
author_sort Li, Yu-Feng
collection PubMed
description The title compound, C(20)H(25)NO(4), was synthesized by a Mitsunobu reaction of sinomenine [(9S,13R,14R)-7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one] with methanol. The chiral centers were unchanged during the reaction. Intra­molecular C—H⋯O hydrogen bonds result in the formation of six-membered rings.
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spelling pubmed-29690832010-12-30 (9S,13R,14R)-7,8-Didehydro-3,4,7-trimeth­oxy-17-methyl­morphinan-6-one Li, Yu-Feng Qian, Yi Yin, Li-He Lv, Ran Zhu, Hong-Jun Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(20)H(25)NO(4), was synthesized by a Mitsunobu reaction of sinomenine [(9S,13R,14R)-7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methylmorphinan-6-one] with methanol. The chiral centers were unchanged during the reaction. Intra­molecular C—H⋯O hydrogen bonds result in the formation of six-membered rings. International Union of Crystallography 2009-03-06 /pmc/articles/PMC2969083/ /pubmed/21582431 http://dx.doi.org/10.1107/S1600536808040749 Text en © Li et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Li, Yu-Feng
Qian, Yi
Yin, Li-He
Lv, Ran
Zhu, Hong-Jun
(9S,13R,14R)-7,8-Didehydro-3,4,7-trimeth­oxy-17-methyl­morphinan-6-one
title (9S,13R,14R)-7,8-Didehydro-3,4,7-trimeth­oxy-17-methyl­morphinan-6-one
title_full (9S,13R,14R)-7,8-Didehydro-3,4,7-trimeth­oxy-17-methyl­morphinan-6-one
title_fullStr (9S,13R,14R)-7,8-Didehydro-3,4,7-trimeth­oxy-17-methyl­morphinan-6-one
title_full_unstemmed (9S,13R,14R)-7,8-Didehydro-3,4,7-trimeth­oxy-17-methyl­morphinan-6-one
title_short (9S,13R,14R)-7,8-Didehydro-3,4,7-trimeth­oxy-17-methyl­morphinan-6-one
title_sort (9s,13r,14r)-7,8-didehydro-3,4,7-trimeth­oxy-17-methyl­morphinan-6-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2969083/
https://www.ncbi.nlm.nih.gov/pubmed/21582431
http://dx.doi.org/10.1107/S1600536808040749
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