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Ethyl 1-(2-bromo­propano­yl)-4-hydr­oxy-2,6-diphenyl-1,2,5,6-tetra­hydro­pyridine-3-carboxylate

The title compound, C(23)H(24)BrNO(4), crystallizes with two independent mol­ecules per asymmetric unit. The methyl group of the ethoxy­carbonyl unit is disordered over two positions, with occupancies of 0.715 (12) and 0.285 (12) in one of the independent mol­ecules, and 0.529 (11) and 0.471 (11) in...

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Detalles Bibliográficos
Autores principales: Aridoss, G., Gayathri, D., Velmurugan, D., Kim, M. S., Jeong, Yeon Tae
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2969390/
https://www.ncbi.nlm.nih.gov/pubmed/21582960
http://dx.doi.org/10.1107/S1600536809023836
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author Aridoss, G.
Gayathri, D.
Velmurugan, D.
Kim, M. S.
Jeong, Yeon Tae
author_facet Aridoss, G.
Gayathri, D.
Velmurugan, D.
Kim, M. S.
Jeong, Yeon Tae
author_sort Aridoss, G.
collection PubMed
description The title compound, C(23)H(24)BrNO(4), crystallizes with two independent mol­ecules per asymmetric unit. The methyl group of the ethoxy­carbonyl unit is disordered over two positions, with occupancies of 0.715 (12) and 0.285 (12) in one of the independent mol­ecules, and 0.529 (11) and 0.471 (11) in the other mol­ecule. In one of the independent mol­ecules, the tetra­hydro­pyridine ring adopts a half-chair conformation, while in the other it is in a distorted envelope conformation. In each independent mol­ecule, an intra­molecular O—H⋯O hydrogen bond generates an S(6) ring motif. The two independent mol­ecules are linked via C—H⋯O hydrogen bonds, forming a chain along the c axis.
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spelling pubmed-29693902010-12-30 Ethyl 1-(2-bromo­propano­yl)-4-hydr­oxy-2,6-diphenyl-1,2,5,6-tetra­hydro­pyridine-3-carboxylate Aridoss, G. Gayathri, D. Velmurugan, D. Kim, M. S. Jeong, Yeon Tae Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(23)H(24)BrNO(4), crystallizes with two independent mol­ecules per asymmetric unit. The methyl group of the ethoxy­carbonyl unit is disordered over two positions, with occupancies of 0.715 (12) and 0.285 (12) in one of the independent mol­ecules, and 0.529 (11) and 0.471 (11) in the other mol­ecule. In one of the independent mol­ecules, the tetra­hydro­pyridine ring adopts a half-chair conformation, while in the other it is in a distorted envelope conformation. In each independent mol­ecule, an intra­molecular O—H⋯O hydrogen bond generates an S(6) ring motif. The two independent mol­ecules are linked via C—H⋯O hydrogen bonds, forming a chain along the c axis. International Union of Crystallography 2009-06-27 /pmc/articles/PMC2969390/ /pubmed/21582960 http://dx.doi.org/10.1107/S1600536809023836 Text en © Aridoss et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Aridoss, G.
Gayathri, D.
Velmurugan, D.
Kim, M. S.
Jeong, Yeon Tae
Ethyl 1-(2-bromo­propano­yl)-4-hydr­oxy-2,6-diphenyl-1,2,5,6-tetra­hydro­pyridine-3-carboxylate
title Ethyl 1-(2-bromo­propano­yl)-4-hydr­oxy-2,6-diphenyl-1,2,5,6-tetra­hydro­pyridine-3-carboxylate
title_full Ethyl 1-(2-bromo­propano­yl)-4-hydr­oxy-2,6-diphenyl-1,2,5,6-tetra­hydro­pyridine-3-carboxylate
title_fullStr Ethyl 1-(2-bromo­propano­yl)-4-hydr­oxy-2,6-diphenyl-1,2,5,6-tetra­hydro­pyridine-3-carboxylate
title_full_unstemmed Ethyl 1-(2-bromo­propano­yl)-4-hydr­oxy-2,6-diphenyl-1,2,5,6-tetra­hydro­pyridine-3-carboxylate
title_short Ethyl 1-(2-bromo­propano­yl)-4-hydr­oxy-2,6-diphenyl-1,2,5,6-tetra­hydro­pyridine-3-carboxylate
title_sort ethyl 1-(2-bromo­propano­yl)-4-hydr­oxy-2,6-diphenyl-1,2,5,6-tetra­hydro­pyridine-3-carboxylate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2969390/
https://www.ncbi.nlm.nih.gov/pubmed/21582960
http://dx.doi.org/10.1107/S1600536809023836
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AT velmurugand ethyl12bromopropanoyl4hydroxy26diphenyl1256tetrahydropyridine3carboxylate
AT kimms ethyl12bromopropanoyl4hydroxy26diphenyl1256tetrahydropyridine3carboxylate
AT jeongyeontae ethyl12bromopropanoyl4hydroxy26diphenyl1256tetrahydropyridine3carboxylate