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Ethyl 1-(2-bromopropanoyl)-4-hydroxy-2,6-diphenyl-1,2,5,6-tetrahydropyridine-3-carboxylate
The title compound, C(23)H(24)BrNO(4), crystallizes with two independent molecules per asymmetric unit. The methyl group of the ethoxycarbonyl unit is disordered over two positions, with occupancies of 0.715 (12) and 0.285 (12) in one of the independent molecules, and 0.529 (11) and 0.471 (11) in...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2969390/ https://www.ncbi.nlm.nih.gov/pubmed/21582960 http://dx.doi.org/10.1107/S1600536809023836 |
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author | Aridoss, G. Gayathri, D. Velmurugan, D. Kim, M. S. Jeong, Yeon Tae |
author_facet | Aridoss, G. Gayathri, D. Velmurugan, D. Kim, M. S. Jeong, Yeon Tae |
author_sort | Aridoss, G. |
collection | PubMed |
description | The title compound, C(23)H(24)BrNO(4), crystallizes with two independent molecules per asymmetric unit. The methyl group of the ethoxycarbonyl unit is disordered over two positions, with occupancies of 0.715 (12) and 0.285 (12) in one of the independent molecules, and 0.529 (11) and 0.471 (11) in the other molecule. In one of the independent molecules, the tetrahydropyridine ring adopts a half-chair conformation, while in the other it is in a distorted envelope conformation. In each independent molecule, an intramolecular O—H⋯O hydrogen bond generates an S(6) ring motif. The two independent molecules are linked via C—H⋯O hydrogen bonds, forming a chain along the c axis. |
format | Text |
id | pubmed-2969390 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-29693902010-12-30 Ethyl 1-(2-bromopropanoyl)-4-hydroxy-2,6-diphenyl-1,2,5,6-tetrahydropyridine-3-carboxylate Aridoss, G. Gayathri, D. Velmurugan, D. Kim, M. S. Jeong, Yeon Tae Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(23)H(24)BrNO(4), crystallizes with two independent molecules per asymmetric unit. The methyl group of the ethoxycarbonyl unit is disordered over two positions, with occupancies of 0.715 (12) and 0.285 (12) in one of the independent molecules, and 0.529 (11) and 0.471 (11) in the other molecule. In one of the independent molecules, the tetrahydropyridine ring adopts a half-chair conformation, while in the other it is in a distorted envelope conformation. In each independent molecule, an intramolecular O—H⋯O hydrogen bond generates an S(6) ring motif. The two independent molecules are linked via C—H⋯O hydrogen bonds, forming a chain along the c axis. International Union of Crystallography 2009-06-27 /pmc/articles/PMC2969390/ /pubmed/21582960 http://dx.doi.org/10.1107/S1600536809023836 Text en © Aridoss et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Aridoss, G. Gayathri, D. Velmurugan, D. Kim, M. S. Jeong, Yeon Tae Ethyl 1-(2-bromopropanoyl)-4-hydroxy-2,6-diphenyl-1,2,5,6-tetrahydropyridine-3-carboxylate |
title | Ethyl 1-(2-bromopropanoyl)-4-hydroxy-2,6-diphenyl-1,2,5,6-tetrahydropyridine-3-carboxylate |
title_full | Ethyl 1-(2-bromopropanoyl)-4-hydroxy-2,6-diphenyl-1,2,5,6-tetrahydropyridine-3-carboxylate |
title_fullStr | Ethyl 1-(2-bromopropanoyl)-4-hydroxy-2,6-diphenyl-1,2,5,6-tetrahydropyridine-3-carboxylate |
title_full_unstemmed | Ethyl 1-(2-bromopropanoyl)-4-hydroxy-2,6-diphenyl-1,2,5,6-tetrahydropyridine-3-carboxylate |
title_short | Ethyl 1-(2-bromopropanoyl)-4-hydroxy-2,6-diphenyl-1,2,5,6-tetrahydropyridine-3-carboxylate |
title_sort | ethyl 1-(2-bromopropanoyl)-4-hydroxy-2,6-diphenyl-1,2,5,6-tetrahydropyridine-3-carboxylate |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2969390/ https://www.ncbi.nlm.nih.gov/pubmed/21582960 http://dx.doi.org/10.1107/S1600536809023836 |
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