Cargando…

5-Hydr­oxy-1,7-bis­(1H-indol-3-yl)hepta-1,4,6-trien-3-one hemihydrate

The title compound, C(23)H(18)N(2)O(2)·0.5H(2)O, a derivative of the biologically active compound curcumin, crystallizes with two organic mol­ecules and a solvent water mol­ecule in the asymmetric unit. Each of the two independent mol­ecules is close to being planar (the dihedral angles between the...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Jun-Hai, Sun, Gang-Chun, Mague, Joel T., Xie, Jing-Xi
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2969607/
https://www.ncbi.nlm.nih.gov/pubmed/21583252
http://dx.doi.org/10.1107/S1600536809018571
Descripción
Sumario:The title compound, C(23)H(18)N(2)O(2)·0.5H(2)O, a derivative of the biologically active compound curcumin, crystallizes with two organic mol­ecules and a solvent water mol­ecule in the asymmetric unit. Each of the two independent mol­ecules is close to being planar (the dihedral angles between the indole ring systems are approximately 9 and 12°) and each exists in the keto–enol form. There is an intra­molecular O—H⋯O hydrogen bond between the keto and enol groups. In the crystal, the components interact by way of N—H⋯N, N—H⋯O and O—H⋯O hydrogen bonds.