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(7R,8S,8aS)-8-Hydr­oxy-7-phenyl­perhydro­indolizin-3-one

In the title compound, C(14)H(17)NO(2), the six-membered ring of the indolizine system adopts a chair conformation. In the crystal, mol­ecules form chains parallel to the b axis via inter­molecular O—H⋯O hydrogen bonds. The absolute mol­ecular configuration was assigned from the synthesis.

Detalles Bibliográficos
Autores principales: Švorc, Ľubomír, Vrábel, Viktor, Marchalín, Štefan, Šafář, Peter, Kožíšek, Jozef
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2969627/
https://www.ncbi.nlm.nih.gov/pubmed/21583218
http://dx.doi.org/10.1107/S1600536809018455
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author Švorc, Ľubomír
Vrábel, Viktor
Marchalín, Štefan
Šafář, Peter
Kožíšek, Jozef
author_facet Švorc, Ľubomír
Vrábel, Viktor
Marchalín, Štefan
Šafář, Peter
Kožíšek, Jozef
author_sort Švorc, Ľubomír
collection PubMed
description In the title compound, C(14)H(17)NO(2), the six-membered ring of the indolizine system adopts a chair conformation. In the crystal, mol­ecules form chains parallel to the b axis via inter­molecular O—H⋯O hydrogen bonds. The absolute mol­ecular configuration was assigned from the synthesis.
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spelling pubmed-29696272010-12-30 (7R,8S,8aS)-8-Hydr­oxy-7-phenyl­perhydro­indolizin-3-one Švorc, Ľubomír Vrábel, Viktor Marchalín, Štefan Šafář, Peter Kožíšek, Jozef Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(14)H(17)NO(2), the six-membered ring of the indolizine system adopts a chair conformation. In the crystal, mol­ecules form chains parallel to the b axis via inter­molecular O—H⋯O hydrogen bonds. The absolute mol­ecular configuration was assigned from the synthesis. International Union of Crystallography 2009-05-23 /pmc/articles/PMC2969627/ /pubmed/21583218 http://dx.doi.org/10.1107/S1600536809018455 Text en © Švorc et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Švorc, Ľubomír
Vrábel, Viktor
Marchalín, Štefan
Šafář, Peter
Kožíšek, Jozef
(7R,8S,8aS)-8-Hydr­oxy-7-phenyl­perhydro­indolizin-3-one
title (7R,8S,8aS)-8-Hydr­oxy-7-phenyl­perhydro­indolizin-3-one
title_full (7R,8S,8aS)-8-Hydr­oxy-7-phenyl­perhydro­indolizin-3-one
title_fullStr (7R,8S,8aS)-8-Hydr­oxy-7-phenyl­perhydro­indolizin-3-one
title_full_unstemmed (7R,8S,8aS)-8-Hydr­oxy-7-phenyl­perhydro­indolizin-3-one
title_short (7R,8S,8aS)-8-Hydr­oxy-7-phenyl­perhydro­indolizin-3-one
title_sort (7r,8s,8as)-8-hydr­oxy-7-phenyl­perhydro­indolizin-3-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2969627/
https://www.ncbi.nlm.nih.gov/pubmed/21583218
http://dx.doi.org/10.1107/S1600536809018455
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