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Ethyl 4-[3,5-bis(trifluoromethyl)phenyl]-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
In the title compound, C(16)H(14)F(6)N(2)O(3), the dihydropyrimidinone ring adopts an envelope conformation. In the crystal, molecules are linked by N—H⋯O and C—H⋯O hydrogen bonds into a ribbon-like structure along the b axis. In the ribbon, a pair of bifurcated acceptor N—H⋯O and C—H⋯O bonds ge...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2969686/ https://www.ncbi.nlm.nih.gov/pubmed/21583249 http://dx.doi.org/10.1107/S1600536809019035 |
| _version_ | 1782190227527303168 |
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| author | Fun, Hoong-Kun Quah, Ching Kheng Babu, M. Kalluraya, B. |
| author_facet | Fun, Hoong-Kun Quah, Ching Kheng Babu, M. Kalluraya, B. |
| author_sort | Fun, Hoong-Kun |
| collection | PubMed |
| description | In the title compound, C(16)H(14)F(6)N(2)O(3), the dihydropyrimidinone ring adopts an envelope conformation. In the crystal, molecules are linked by N—H⋯O and C—H⋯O hydrogen bonds into a ribbon-like structure along the b axis. In the ribbon, a pair of bifurcated acceptor N—H⋯O and C—H⋯O bonds generate an R (2) (1)(6) ring motif. Adjacent ribbons are linked via C—H⋯F hydrogen bonds. |
| format | Text |
| id | pubmed-2969686 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2009 |
| publisher | International Union of Crystallography |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-29696862010-12-30 Ethyl 4-[3,5-bis(trifluoromethyl)phenyl]-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate Fun, Hoong-Kun Quah, Ching Kheng Babu, M. Kalluraya, B. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(16)H(14)F(6)N(2)O(3), the dihydropyrimidinone ring adopts an envelope conformation. In the crystal, molecules are linked by N—H⋯O and C—H⋯O hydrogen bonds into a ribbon-like structure along the b axis. In the ribbon, a pair of bifurcated acceptor N—H⋯O and C—H⋯O bonds generate an R (2) (1)(6) ring motif. Adjacent ribbons are linked via C—H⋯F hydrogen bonds. International Union of Crystallography 2009-05-29 /pmc/articles/PMC2969686/ /pubmed/21583249 http://dx.doi.org/10.1107/S1600536809019035 Text en © Fun et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
| spellingShingle | Organic Papers Fun, Hoong-Kun Quah, Ching Kheng Babu, M. Kalluraya, B. Ethyl 4-[3,5-bis(trifluoromethyl)phenyl]-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate |
| title | Ethyl 4-[3,5-bis(trifluoromethyl)phenyl]-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate |
| title_full | Ethyl 4-[3,5-bis(trifluoromethyl)phenyl]-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate |
| title_fullStr | Ethyl 4-[3,5-bis(trifluoromethyl)phenyl]-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate |
| title_full_unstemmed | Ethyl 4-[3,5-bis(trifluoromethyl)phenyl]-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate |
| title_short | Ethyl 4-[3,5-bis(trifluoromethyl)phenyl]-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate |
| title_sort | ethyl 4-[3,5-bis(trifluoromethyl)phenyl]-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate |
| topic | Organic Papers |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2969686/ https://www.ncbi.nlm.nih.gov/pubmed/21583249 http://dx.doi.org/10.1107/S1600536809019035 |
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