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Methyl trans-(±)-1-oxo-2-phenethyl-3-(thio­phen-2-yl)-1,2,3,4-tetra­hydro­isoquinoline-4-carboxyl­ate

In the title compound, C(23)H(21)NO(3)S, the piperidine ring of the tetra­hydro­isoquinolinone unit adopts a screw-boat conformation. The thio­phene ring is disordered in a 0.700 (3):0.300 (3) ratio by an approximate 180° rotation of the ring around the C—C bond linking the ring to the tetra­hydro­i...

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Detalles Bibliográficos
Autores principales: Akkurt, Mehmet, Karaca, Selvi, Bogdanov, Milen G., Kandinska, Meglena I., Büyükgüngör, Orhan
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2969771/
https://www.ncbi.nlm.nih.gov/pubmed/21583149
http://dx.doi.org/10.1107/S1600536809017383
Descripción
Sumario:In the title compound, C(23)H(21)NO(3)S, the piperidine ring of the tetra­hydro­isoquinolinone unit adopts a screw-boat conformation. The thio­phene ring is disordered in a 0.700 (3):0.300 (3) ratio by an approximate 180° rotation of the ring around the C—C bond linking the ring to the tetra­hydro­isoquinolinone unit. The benzene ring of the tetra­hydro­isoquinolinone unit makes dihedral angles of 83.1 (2) and 62.38 (11)° with the major occupancy thio­phene ring and the phenyl ring, respectively. The dihedral angle between the phenyl ring and the thio­phene ring is 71.0 (2)°. In the crystal structure, mol­ecules are linked together by inter­molecular C—H⋯O and C—H⋯π inter­actions.