Ethyl 4-(2,4-difluoro­phen­yl)-6-methyl-2-oxo-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate

In the title compound, C(14)H(14)F(2)N(2)O(3), the dihydro­pyrimidin­one ring adopts a flattened boat conformation. The difluoro­phenyl group is disordered over two orientations with occupancies of 0.544 (3) and 0.456 (3). The methoxy­carbonyl group is disordered over two positions with occupancies...

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Detalles Bibliográficos
Autores principales: Fun, Hoong-Kun, Yeap, Chin Sing, Babu, M., Kalluraya, B.
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2969791/
https://www.ncbi.nlm.nih.gov/pubmed/21583061
http://dx.doi.org/10.1107/S1600536809015918
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author Fun, Hoong-Kun
Yeap, Chin Sing
Babu, M.
Kalluraya, B.
author_facet Fun, Hoong-Kun
Yeap, Chin Sing
Babu, M.
Kalluraya, B.
author_sort Fun, Hoong-Kun
collection PubMed
description In the title compound, C(14)H(14)F(2)N(2)O(3), the dihydro­pyrimidin­one ring adopts a flattened boat conformation. The difluoro­phenyl group is disordered over two orientations with occupancies of 0.544 (3) and 0.456 (3). The methoxy­carbonyl group is disordered over two positions with occupancies of 0.580 (8) and 0.420 (8). In the crystal, mol­ecules are linked into centrosymmetric dimers by paired N—H⋯O hydrogen bonds and the dimers are linked into a ribbon-like structure along [100] by further N—H⋯O hydrogen bonds.
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spelling pubmed-29697912010-12-30 Ethyl 4-(2,4-difluoro­phen­yl)-6-methyl-2-oxo-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate Fun, Hoong-Kun Yeap, Chin Sing Babu, M. Kalluraya, B. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(14)H(14)F(2)N(2)O(3), the dihydro­pyrimidin­one ring adopts a flattened boat conformation. The difluoro­phenyl group is disordered over two orientations with occupancies of 0.544 (3) and 0.456 (3). The methoxy­carbonyl group is disordered over two positions with occupancies of 0.580 (8) and 0.420 (8). In the crystal, mol­ecules are linked into centrosymmetric dimers by paired N—H⋯O hydrogen bonds and the dimers are linked into a ribbon-like structure along [100] by further N—H⋯O hydrogen bonds. International Union of Crystallography 2009-05-07 /pmc/articles/PMC2969791/ /pubmed/21583061 http://dx.doi.org/10.1107/S1600536809015918 Text en © Fun et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Fun, Hoong-Kun
Yeap, Chin Sing
Babu, M.
Kalluraya, B.
Ethyl 4-(2,4-difluoro­phen­yl)-6-methyl-2-oxo-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate
title Ethyl 4-(2,4-difluoro­phen­yl)-6-methyl-2-oxo-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate
title_full Ethyl 4-(2,4-difluoro­phen­yl)-6-methyl-2-oxo-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate
title_fullStr Ethyl 4-(2,4-difluoro­phen­yl)-6-methyl-2-oxo-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate
title_full_unstemmed Ethyl 4-(2,4-difluoro­phen­yl)-6-methyl-2-oxo-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate
title_short Ethyl 4-(2,4-difluoro­phen­yl)-6-methyl-2-oxo-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate
title_sort ethyl 4-(2,4-difluoro­phen­yl)-6-methyl-2-oxo-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2969791/
https://www.ncbi.nlm.nih.gov/pubmed/21583061
http://dx.doi.org/10.1107/S1600536809015918
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