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Ethyl 2-(2,6-difluorobenzyloxy)-4-(4,6-dimethoxypyrimidin-2-yl)quinoline-3-carboxylate
In the title compound, C(25)H(21)F(2)N(3)O(5), the pyrimidine and difluorobenzyloxy rings are twisted away from the central quinoline ring system, making dihedral angles of 54.6 (1) and 74.1 (1)°, respectively. A weak C—H⋯O interaction links symmetry-related molecules, forming a pseudo-dimer. π–...
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970014/ https://www.ncbi.nlm.nih.gov/pubmed/21577516 http://dx.doi.org/10.1107/S1600536809030499 |
Sumario: | In the title compound, C(25)H(21)F(2)N(3)O(5), the pyrimidine and difluorobenzyloxy rings are twisted away from the central quinoline ring system, making dihedral angles of 54.6 (1) and 74.1 (1)°, respectively. A weak C—H⋯O interaction links symmetry-related molecules, forming a pseudo-dimer. π–π interactions between the quinoline rings of symmetry-related molecules [centroid–centroid distance = 3.5479 (10) Å] link these dimers into chains parallel to [101]. Weak C—H⋯π interactions join adjacent chains, forming a two-dimensional layer parallel to (101). |
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