5-Amino-1-phenyl-3-trifluoro­methyl-1H-pyrazole-4-carboxylic acid

In the title compound, C(11)H(8)F(3)N(3)O(2), there are two mol­ecules in the asymmetric unit wherein the phenyl rings make dihedral angles of 65.3 (2) and 85.6 (2)° with the pyrazole rings. In the crystal, pairs of mol­ecules are held together by O—H⋯O hydrogen bonds between the carboxyl groups, fo...

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Autores principales: Caruso, Francesco, Raimondi, Maria Valeria, Daidone, Giuseppe, Pettinari, Claudio, Rossi, Miriam
Formato: Texto
Lenguaje:English
Publicado: International Union of Crystallography 2009
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970016/
https://www.ncbi.nlm.nih.gov/pubmed/21577579
http://dx.doi.org/10.1107/S1600536809032188
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author Caruso, Francesco
Raimondi, Maria Valeria
Daidone, Giuseppe
Pettinari, Claudio
Rossi, Miriam
author_facet Caruso, Francesco
Raimondi, Maria Valeria
Daidone, Giuseppe
Pettinari, Claudio
Rossi, Miriam
author_sort Caruso, Francesco
collection PubMed
description In the title compound, C(11)H(8)F(3)N(3)O(2), there are two mol­ecules in the asymmetric unit wherein the phenyl rings make dihedral angles of 65.3 (2) and 85.6 (2)° with the pyrazole rings. In the crystal, pairs of mol­ecules are held together by O—H⋯O hydrogen bonds between the carboxyl groups, forming a centrosymmetric dimer with an R (2) (2)(8) motif. Intra­molecular N—H⋯O inter­actions are also present.
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spelling pubmed-29700162010-12-30 5-Amino-1-phenyl-3-trifluoro­methyl-1H-pyrazole-4-carboxylic acid Caruso, Francesco Raimondi, Maria Valeria Daidone, Giuseppe Pettinari, Claudio Rossi, Miriam Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(11)H(8)F(3)N(3)O(2), there are two mol­ecules in the asymmetric unit wherein the phenyl rings make dihedral angles of 65.3 (2) and 85.6 (2)° with the pyrazole rings. In the crystal, pairs of mol­ecules are held together by O—H⋯O hydrogen bonds between the carboxyl groups, forming a centrosymmetric dimer with an R (2) (2)(8) motif. Intra­molecular N—H⋯O inter­actions are also present. International Union of Crystallography 2009-08-15 /pmc/articles/PMC2970016/ /pubmed/21577579 http://dx.doi.org/10.1107/S1600536809032188 Text en © Caruso et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Caruso, Francesco
Raimondi, Maria Valeria
Daidone, Giuseppe
Pettinari, Claudio
Rossi, Miriam
5-Amino-1-phenyl-3-trifluoro­methyl-1H-pyrazole-4-carboxylic acid
title 5-Amino-1-phenyl-3-trifluoro­methyl-1H-pyrazole-4-carboxylic acid
title_full 5-Amino-1-phenyl-3-trifluoro­methyl-1H-pyrazole-4-carboxylic acid
title_fullStr 5-Amino-1-phenyl-3-trifluoro­methyl-1H-pyrazole-4-carboxylic acid
title_full_unstemmed 5-Amino-1-phenyl-3-trifluoro­methyl-1H-pyrazole-4-carboxylic acid
title_short 5-Amino-1-phenyl-3-trifluoro­methyl-1H-pyrazole-4-carboxylic acid
title_sort 5-amino-1-phenyl-3-trifluoro­methyl-1h-pyrazole-4-carboxylic acid
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970016/
https://www.ncbi.nlm.nih.gov/pubmed/21577579
http://dx.doi.org/10.1107/S1600536809032188
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AT pettinariclaudio 5amino1phenyl3trifluoromethyl1hpyrazole4carboxylicacid
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