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Memantinium chloride 0.1-hydrate
The crystal structure of the title compound, C(12)H(22)N(+)·Cl(−)·0.1H(2)O, consists of (3,5-dimethyl-1-adamantyl)ammonium chloride (memantinium chloride) and uncoordinated water molecules. The four six-membered rings of the memantinium cation assume typical chair conformations. The Cl(−) counter...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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International Union of Crystallography
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970061/ https://www.ncbi.nlm.nih.gov/pubmed/21577595 http://dx.doi.org/10.1107/S1600536809031791 |
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author | Lou, Wei-Jian Hu, Xiu-Rong Gu, Jian-Ming |
author_facet | Lou, Wei-Jian Hu, Xiu-Rong Gu, Jian-Ming |
author_sort | Lou, Wei-Jian |
collection | PubMed |
description | The crystal structure of the title compound, C(12)H(22)N(+)·Cl(−)·0.1H(2)O, consists of (3,5-dimethyl-1-adamantyl)ammonium chloride (memantinium chloride) and uncoordinated water molecules. The four six-membered rings of the memantinium cation assume typical chair conformations. The Cl(−) counter-anion links with the memantinium cation via N—H⋯Cl hydrogen bonding, forming channels where the disordered crystal water molecules are located. The O atom of the water molecule is located on a threefold rotation axis, its two H atoms symmetrically distributed over six sites; the water molecule links with the Cl(−) anions via O—H⋯Cl hydrogen bonding. |
format | Text |
id | pubmed-2970061 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-29700612010-12-30 Memantinium chloride 0.1-hydrate Lou, Wei-Jian Hu, Xiu-Rong Gu, Jian-Ming Acta Crystallogr Sect E Struct Rep Online Organic Papers The crystal structure of the title compound, C(12)H(22)N(+)·Cl(−)·0.1H(2)O, consists of (3,5-dimethyl-1-adamantyl)ammonium chloride (memantinium chloride) and uncoordinated water molecules. The four six-membered rings of the memantinium cation assume typical chair conformations. The Cl(−) counter-anion links with the memantinium cation via N—H⋯Cl hydrogen bonding, forming channels where the disordered crystal water molecules are located. The O atom of the water molecule is located on a threefold rotation axis, its two H atoms symmetrically distributed over six sites; the water molecule links with the Cl(−) anions via O—H⋯Cl hydrogen bonding. International Union of Crystallography 2009-08-19 /pmc/articles/PMC2970061/ /pubmed/21577595 http://dx.doi.org/10.1107/S1600536809031791 Text en © Lou et al. 2009 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Lou, Wei-Jian Hu, Xiu-Rong Gu, Jian-Ming Memantinium chloride 0.1-hydrate |
title | Memantinium chloride 0.1-hydrate |
title_full | Memantinium chloride 0.1-hydrate |
title_fullStr | Memantinium chloride 0.1-hydrate |
title_full_unstemmed | Memantinium chloride 0.1-hydrate |
title_short | Memantinium chloride 0.1-hydrate |
title_sort | memantinium chloride 0.1-hydrate |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2970061/ https://www.ncbi.nlm.nih.gov/pubmed/21577595 http://dx.doi.org/10.1107/S1600536809031791 |
work_keys_str_mv | AT louweijian memantiniumchloride01hydrate AT huxiurong memantiniumchloride01hydrate AT gujianming memantiniumchloride01hydrate |